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GlossaryLeydig Cell Tumor

rare testicular tumor from testosterone-producing Leydig cells

A Leydig Cell Tumor is a rare type of tumor that originates from the Leydig cells, which are found in the testes and are responsible for producing testosterone. These tumors can occur in both children and adults and may cause symptoms such as testicular swelling, pain, or hormonal imbalances. While most Leydig Cell Tumors are benign, a small percentage can be malignant and may require surgical removal and further treatment.

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Menopausal Androgen Excess-Associated Cardio-Metabolic Risk: Clues for Ovarian Leydig Cell Tumor (Case Report and Mini-Review of Literature)

research Menopausal Androgen Excess-Associated Cardio-Metabolic Risk: Clues for Ovarian Leydig Cell Tumor (Case Report and Mini-Review of Literature)

5 citations, January 2017 in “Acta Endocrinologica”

High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.

research Finasteride-Related Leydig Cell Tumor: Report of a Case and Literature Review

5 citations, May 2012 in “Andrologia”

Finasteride use may be linked to rare testicular tumor, but more research needed.

research Diagnostic Pitfalls in Ovarian Androgen-Secreting (Leydig Cell) Tumors: Case Series

5 citations, November 2018 in “Journal of Obstetrics and Gynaecology”

Ovarian Leydig cell tumors are hard to diagnose with just advanced imaging; expert ultrasound and clinical evaluation are essential.

research Sertoli-Leydig Cell Ovarian Tumor: A Rare Cause of Virilization and Androgenic Alopecia

1 citations, August 2022 in “Case Reports”

A rare ovarian tumor caused high testosterone, hair loss, and missed periods, but surgery fixed these issues and led to pregnancy.

research Sertoli-Leydig Cell Tumor: A Rare Cause of Androgenic Alopecia in Postmenopausal Women

October 2012 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism”

A rare ovarian tumor caused hair loss in a post-menopausal woman, which almost completely stopped after surgery.

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community Mechanism of action of alfatradiol (17 alpha estradiol)

in Research/Science 6 upvotes 5 months ago

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

community FtM: "Aggressive Regemin - Recovery From Norwood-6.5" Minoxodil/Estradiol valerate/Spironolactone. (What will happen in the worst case if CIS male go this way for a year?)

in Progress Pictures 54 upvotes 3 years ago

User "Ant1pal" shares progress pictures of hair regrowth using Minoxidil, Estradiol valerate, and Spironolactone. Users discuss potential side effects and the possibility of localizing estrogen to hair follicles for better treatment.

community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

in Research/Science 37 upvotes 2 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.