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GlossaryLeydig Cell Tumor

rare testicular tumor from testosterone-producing Leydig cells

A Leydig Cell Tumor is a rare type of tumor that originates from the Leydig cells, which are found in the testes and are responsible for producing testosterone. These tumors can occur in both children and adults and may cause symptoms such as testicular swelling, pain, or hormonal imbalances. While most Leydig Cell Tumors are benign, a small percentage can be malignant and may require surgical removal and further treatment.

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research An Occult Leydig Cell Tumor in a Postmenopausal Woman Presenting with Alopecia and Hirsutism: A Case Report

3 citations , January 2021 in “touchREVIEWS in Endocrinology”

Surgery removed an ovarian tumor, improving her symptoms and normalizing testosterone levels.

research Finasteride-Related Leydig Cell Tumor: Report of a Case and Literature Review

5 citations , September 2011 in “Andrologia”

Finasteride use may be linked to rare testicular tumor, but more research needed.

research Virilizing Ovarian Tumor in a Woman with an Adrenal Nodule

6 citations , January 2010 in “Case Reports”

A woman with high testosterone and an adrenal nodule had an ovarian tumor causing her symptoms, which improved after the tumor was removed.

research Steroid Cell Tumors: Rare Ovarian Tumors That Cause Hyperandrogenemia in Postmenopausal Women

December 2020 in “Research Square (Research Square)”

Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.

research An Occult Leydig Cell Tumor in a Postmenopausal Woman Presenting with Alopecia and Hirsutism: A Case Report

January 2021 in “touchREVIEWS in Endocrinology”

Surgery successfully treated a hidden ovarian tumor causing hair loss and excess hair growth in a postmenopausal woman.

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community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

in Research/Science 37 upvotes 3 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

community Mechanism of action of alfatradiol (17 alpha estradiol)

in Research/Science 6 upvotes 1 year ago

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

community FtM: "Aggressive Regemin - Recovery From Norwood-6.5" Minoxodil/Estradiol valerate/Spironolactone. (What will happen in the worst case if CIS male go this way for a year?)

in Progress Pictures 56 upvotes 4 years ago

User "Ant1pal" shares progress pictures of hair regrowth using Minoxidil, Estradiol valerate, and Spironolactone. Users discuss potential side effects and the possibility of localizing estrogen to hair follicles for better treatment.