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    GlossaryHair Growth Mechanisms (hair growth pathways)

    biological processes regulating hair follicle development and cycling

    Hair Growth Mechanisms refer to the biological processes and pathways that regulate the development, growth, and shedding of hair. These mechanisms involve a complex interplay of genetic, hormonal, and environmental factors that influence the hair follicle cycle, which includes the anagen (growth), catagen (regression), and telogen (resting) phases. Understanding these mechanisms is crucial for developing treatments for hair loss conditions like alopecia.

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      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

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      an anticonvulsant repurposed for hair loss via histone inhibition

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      popular antihistamine showing promise for hair loss as an anti-inflammatory and prostaglandin inhibitor

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials