Search

for
Search:

GlossaryLaser Capture Microdissection (LCM)

technique using a laser to isolate specific cells from tissue

Laser Capture Microdissection (LCM) is a technique used to precisely isolate specific cells or regions from a tissue sample using a laser. This allows researchers to study the genetic material, proteins, or other cellular components of the selected cells without contamination from surrounding tissues, making it particularly useful in fields like cancer research and pathology.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 116 results

research Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.

research 555 Dermal Single-Cell Atlas: A Novel Tool to Explore Fibroblast Heterogeneity

November 2022 in “Journal of Investigative Dermatology”

A new tool helps study hair follicle cells to develop better treatments for hair disorders.

Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells

research Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells

16 citations, January 2007 in “Dermatology”

Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

research Mutations in the Vitamin D Receptor Gene in Four Patients with Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets

24 citations, November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia”

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors

37 citations, September 2018 in “The Journal of Clinical Endocrinology and Metabolism”

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

View more "lcm" in research →

Community Join

5 / 7 results

community Guide To Finasteride and Avoiding Side Effects

in Finasteride/Dutasteride 23 upvotes 2 years ago

The conversation provides a guide on using finasteride for hair loss, suggesting to start with a quarter of a 1mg pill daily after ensuring estradiol levels are within a specific range, and potentially increasing the dose if no side effects occur. It also recommends supplements like DIM, Calcium d-glucarate, and Zinc to manage high estradiol levels and side effects from finasteride.

community Feel like I'm a reasonably good responder

in Is this regrowth? 274 upvotes 4 months ago

The user "OP" reported significant hair regrowth using oral finasteride, oral and topical minoxidil, ketoconazole shampoo, and derma stamping. OP experienced initial shedding but no other side effects.

community 9 months on dut. Loosing ground with 150-250+ hairs everyday.

in Finasteride/Dutasteride 11 upvotes 6 months ago

A user reported losing 150-250 hairs daily after 9 months on dutasteride, despite previously stabilizing hair loss with finasteride and minoxidil. Blood tests showed high DHT levels, and the user is unsure if they should continue the current treatment.

community Serum DHT levels variation on dutasteride

in Treatment 1 year ago

Serum DHT levels and their variations when using dutasteride for hair loss treatment.

community My DHT levels have increased after taking 0.25mg Fin for 47 days!

in Finasteride/Dutasteride 185 upvotes 2 months ago

A user experienced increased hair shedding and unchanged DHT levels after taking 0.25mg of finasteride for 47 days, leading them to increase the dose to 0.5mg. Others discussed varying experiences with finasteride, minoxidil, and the importance of measuring scalp DHT.

View more "lcm" in community →