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GlossaryLaser Capture Microdissection (LCM)

technique using a laser to isolate specific cells from tissue

Laser Capture Microdissection (LCM) is a technique used to precisely isolate specific cells or regions from a tissue sample using a laser. This allows researchers to study the genetic material, proteins, or other cellular components of the selected cells without contamination from surrounding tissues, making it particularly useful in fields like cancer research and pathology.

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research Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.

research 555 Dermal Single-Cell Atlas: A Novel Tool to Explore Fibroblast Heterogeneity

November 2022 in “Journal of Investigative Dermatology”

A new tool helps study hair follicle cells to develop better treatments for hair disorders.

Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells

research Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells

16 citations , January 2007 in “Dermatology”

Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

research The Effective Course of Finasteride Pretreatment in Decreasing Blood Loss Associated with TURP

January 2005 in “Journal of Clinical Urology”

Taking finasteride for at least 3 months before TURP reduces blood loss.

research Mutations in the Vitamin D Receptor Gene in Four Patients with Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets

24 citations , November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia”

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

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community Guide To Finasteride and Avoiding Side Effects

in Finasteride/Dutasteride 26 upvotes 3 years ago

The conversation provides a guide on using finasteride for hair loss, suggesting to start with a quarter of a 1mg pill daily after ensuring estradiol levels are within a specific range, and potentially increasing the dose if no side effects occur. It also recommends supplements like DIM, Calcium d-glucarate, and Zinc to manage high estradiol levels and side effects from finasteride.

community Interpreting pre-finisteride blood panels

in Chat 2 upvotes 5 months ago

The conversation is about someone planning to start finasteride for hair loss and wanting to interpret pre-treatment blood panels to assess the risk of side effects like gynecomastia. They list various tests to measure hormone levels and other health indicators.

community Pre-Finisteride DHT & Hormone Blood Panel

in Finasteride/Dutasteride 3 upvotes 6 months ago

The conversation discusses the cost and insurance coverage of a comprehensive hormone and DHT blood panel for hair loss, with a focus on finasteride treatment. The user seeks a cheaper alternative to a $700 panel recommended in a video.

community Feel like I'm a reasonably good responder

in Is this regrowth? 274 upvotes 1 year ago

The user "OP" reported significant hair regrowth using oral finasteride, oral and topical minoxidil, ketoconazole shampoo, and derma stamping. OP experienced initial shedding but no other side effects.

community 9 months on dut. Loosing ground with 150-250+ hairs everyday.

in Finasteride/Dutasteride 11 upvotes 1 year ago

A user reported losing 150-250 hairs daily after 9 months on dutasteride, despite previously stabilizing hair loss with finasteride and minoxidil. Blood tests showed high DHT levels, and the user is unsure if they should continue the current treatment.

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