16 citations
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January 2007 in “Dermatology” This review summarizes recent progress in human hair follicle bulge cell research, particularly the characterization and isolation of these stem cells, but reports no new experimental results.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study generated a transcriptomic map of human hair follicles, identifying compartment-specific gene expression profiles that can aid in developing targeted therapies for hair follicle disorders.
November 2022 in “Journal of Investigative Dermatology” This study generated a transcriptomic map of human hair follicle compartments, providing a database for identifying compartment-specific gene expression which may aid in developing targeted treatments for hair follicle disorders.
8 citations
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March 2023 in “BMC Research Notes” This pilot study explored a new method using laser-capture microdissection and 16S rRNA gene sequencing to analyze the human scalp hair follicle microbiome more accurately, revealing region-specific variations in microbial diversity and abundance.
This study identified new geometric and mechanical parameters for curly and kinky/coily hair, which may inform more effective personal care products tailored to these hair types.
January 2005 in “Journal of Clinical Urology” The study concluded that long-term finasteride pretreatment significantly reduces intraoperative and postoperative blood loss in patients undergoing transurethral resection of an enlarged prostate, whereas short-term pretreatment does not.
13 citations
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January 2015 in “Molecular Pharmaceutics” This study suggests that minoxidil may serve as a suitable reference drug for high permeability classification in the Biopharmaceutics Classification System due to its consistent permeability across different intestinal segments and pH levels.
24 citations
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November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia” In this study, mutations in the vitamin D receptor were identified in Brazilian children with rickets and alopecia, leading to impaired receptor activation and reduced 24-hydroxylase expression.
January 2025 in “Current Trends in Pharmacy and Pharmaceutical Chemistry” This review examines recent advancements in analytical techniques used to quantify dutasteride, a medication for enlarged prostate, in various biological samples and its commercial forms, emphasizing methods such as HPTLC, GC-MS, and HPLC.
37 citations
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September 2018 in “The Journal of Clinical Endocrinology and Metabolism” This study found that intravaginal testosterone significantly improved sexual satisfaction and reduced dyspareunia in postmenopausal women using aromatase inhibitors, with no effect on urinary incontinence.
21 citations
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June 2016 in “Genesis” This study identified a gene expression signature in mouse embryonic dermal fibroblasts that depends on Wnt/β-catenin activity, potentially influencing dermal fibroblast identity and function.
15 citations
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February 2013 in “Pharmaceutical nanotechnology” This study found that invasomes enhanced the iontophoretic transdermal delivery of finasteride in rabbits, increasing AUC and T1/2 compared to oral suspension.
12 citations
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December 2013 in “The Journal of Urology” Men's age, urinary symptoms, and heart health risks create different types of erectile dysfunction.
11 citations
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November 2015 in “Journal of Functional Foods” This study found that the ethyl acetate fraction of Hibiscus rosa sinensis petals significantly reduced serum glucose and glycated hemoglobin levels in diabetic rats, with effects comparable to metformin.
5 citations
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August 2018 This paper highlights the growing scientific interest in plant extracts for cosmetics due to their potential benefits, including antioxidant, antimicrobial, and protective properties, while emphasizing the need for quality and safety assessment to mitigate possible adverse reactions.
November 2022 in “Journal of the Endocrine Society” This case study reports a rare instance of a virilizing androgen-only secreting adrenal cortical adenoma in a 13-year-old, with symptom resolution after surgical removal.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Quantitative Mass Spectrometry Imaging offers precise localization and quantification of active compounds in skin tissues, demonstrating benefits over traditional LC-MS in drug penetration studies.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In a guinea pig model of dermatophytosis, this study found that subcutaneous CD101, dosed once weekly, demonstrated significant clinical and mycological efficacy compared to the vehicle control and the oral antifungal terbinafine, suggesting potential for CD101 in treating fungal skin infections.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that topical Vorinostat induced significant hair regrowth in mice with alopecia areata, suggesting it as a potential repurposable treatment for the condition.
January 1999 in “Current Problems in Pediatrics” Swimming in Lake Malawi can lead to schistosomiasis, hepatitis B vaccine might cause temporary hair loss, and certain drinks affect kidney stone risk.
This study used quantitative methods to identify new geometric and mechanical parameters of curly and kinky/coily hair, aiming to improve classification and develop better personal care products for these hair types.
501 citations
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October 2008 in “Psychoneuroendocrinology” This study suggests that cortisol measured in human hair can effectively reflect increased production for up to six months, but its retrospective accuracy may be limited due to rapid decline in levels.
256 citations
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that altering cell culture conditions to form three-dimensional papilla spheroids can restore the ability of human dermal papilla cells to induce hair growth in adult skin.
136 citations
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April 2013 in “Clinical Cancer Research” The study found that IPI-926 was well tolerated up to 160 mg once daily for 28-day cycles and showed activity as a single-agent treatment in Hedgehog pathway inhibitor-naïve patients with basal cell carcinoma.
113 citations
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July 2020 in “Communications biology” This review suggests that understanding the biological and molecular reasons for more severe COVID-19 in men, particularly those at risk for prostate cancer, could improve management of these patients, but reports no new results.
87 citations
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July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” This review discusses the essential roles and complex regulation of PP2A in various physiological processes and reports no clinical results; the authors highlight the need for further mouse model research to explore PP2A's therapeutic potential.
84 citations
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July 2003 in “European journal of biochemistry” This study found that mouse skin can produce and metabolize serotonin and N-acetylserotonin, with activity influenced by location, physiological skin status, cell type, and mouse strain.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” This research abstract provides no results, focusing on the equal contributions of the authors in the field of molecular, cellular, and developmental biology from Yale University.
70 citations
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April 2014 in “Annales d'endocrinologie” This review discusses the pathways of androgen biosynthesis and reports no new findings, highlighting the need to understand the interplay between the classic and backdoor pathways.
66 citations
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August 2001 in “Experimental Dermatology” This study demonstrated that intact adult human dermal papillae can induce hair growth when implanted into mouse hair follicles, highlighting their potential for advancing hair follicle biology and therapeutic approaches.