April 2025 in “Dermatology Practical & Conceptual” In this study, researchers observed that individuals with premature graying of hair had significantly higher LC3 gene expression compared to controls, suggesting a potential link between autophagy and the development of this condition, with LC3 gene expression as a possible independent predictor.
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May 2020 in “PubMed” This study found that autophagy-related gene expressions in bleomycin-induced mouse skin fibrosis initially increased and then decreased, implying autophagy activation may potentially reverse skin fibrosis.
November 2025 in “Transfusion Medicine and Hemotherapy” This study found that platelet-rich plasma therapy significantly promoted hair growth in androgenetic alopecia model mice by enhancing autophagy, with effects similar to rapamycin treatment.
June 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that anti-Ku-positive patients exhibit heterogeneous muscle features, primarily showing a myositis pattern with necrotizing fibers and vacuolar changes, and suggests autophagy may play a significant role in their pathogenesis.
February 2025 in “Biomolecules” This study found that activation of RORA significantly promotes the level of autophagy in rat hair follicle stem cells, suggesting a potential target for research on hair follicle development and treatments for conditions like alopecia.