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research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Lamins in Development, Tissue Maintenance, and Stress
Lamins are vital for cell survival, organ development, and preventing premature aging.
research Type II Keratins Are Phosphorylated on a Unique Motif During Stress and Mitosis in Tissues and Cultured Cells
Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.
research Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex
Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
research Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
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5 / 23 resultscommunity Just wanted to provide a little reassurance
A user shared their positive experience with a hair loss treatment regimen including Dutasteride, Minoxidil, RU58841, Nizoral, microneedling, and supplements, reporting no side effects and some hair regrowth. They encouraged others not to fear these treatments, as they are generally safe.
community My Hairline journey. The first photo taken is the day I took the pill. No date specific just know I’ve been on finasteride 22 months. 2 years November 14th. ASK ANYTHING. Oh yeah started minoxidil a year later. Once every day or every other day super inconsistent and never really use 1ml, maybe half
. Fin from Inhouse
This user has been taking finasteride for 22 months and minoxidil for 1 year to reduce hair loss, with apparent success; they have also avoided tight cornrow hairstyles to further protect their hairline.
community [M23] AWESOME progress on DUT Mesotherapy until I ruined everything
A user shared their progress with hair loss treatment using Dutasteride Mesotherapy but mentioned they ruined their progress. Another user commented that Minoxidil caused shedding, which should regrow in three months.
community Verteporfin and Microneedling
Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
community Finasteride has not only helped my hairline but also the thickness of my hair and has helped it grow a lot in general over the last 6 months. Thoughts?
Finasteride helping to improve the user's hairline, thickness, and growth over the last 6 months. Other users offered their support and encouragement.