November 2024 in “Traditional & Kampo Medicine” This study found that kumazasa extract promotes hair growth in a mouse model and human hair follicle cells, with effects similar to minoxidil, but it did not cause the inflammation observed with minoxidil use.
In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.
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April 2017 in “Scientific Reports” This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.
June 2025 in “Current Issues in Molecular Biology” In this laboratory study, Cucumis melo var. makuwa leaf extract significantly reduced DHT-induced apoptosis in human dermal papilla cells by modulating androgen receptor activity and gene expression, suggesting potential as a therapy for androgenetic alopecia.
This case study describes a 34-year-old male developing painful inflammatory scalp nodules post-scalp microinfusion of medication. The findings suggest that repeated microtrauma or bacterial colonization might trigger dissecting cellulitis in susceptible individuals, with exogenous testosterone as a potential modifier, not a direct cause.