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      learn KX-826

      • Kintor Pharmaceutical: KX-826, a New Name in Hair Loss Research KX-826 (pyrilutamide) is an experimental topical androgen receptor blocker from Kintor Pharmaceutical. It is not approved as a medicine anywhere; the company reports that its China Phase III trial met its primary endpoint at 24 weeks, but the trial data has been released through corporate announcements rather than peer-reviewed journals and long-term safety is unknown.

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

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      Development and Validation of Androgen-Induced Hair Loss and Anagen Induction Mouse Models for Pharmacological Evaluation of Anti-Androgenic Agents

      research Development and Validation of Androgen-induced Hair Loss and Anagen Induction Mouse Models for Pharmacological Evaluation of Anti-Androgenic Agents

      1 citations , April 2024 in “Journal of Pharmaceutical and Pharmacological Sciences”
      This study evaluated androgen-induced hair loss and anagen induction mouse models, finding that Minoxidil and Pyrilutamide significantly promoted hair growth by decreasing androgen receptor protein levels and enhancing the Wnt/β-Catenin signaling pathway, supporting their use in studying novel treatments for androgenetic alopecia.
      Dermatology

      research Dermatology

      1 citations , February 2004
      This chapter discusses various skin diseases and the adaptation of clinical trial methods to different dermatological conditions, without providing new research findings.
      Folliculitis Keloidalis Nuchae and Pseudofolliculitis Barbae

      research Folliculitis Keloidalis Nuchae and Pseudofolliculitis Barbae

      49 citations , March 2014 in “Dermatologic clinics”
      This article discusses the causes, development, treatment, and prevention strategies for pseudofolliculitis barbae and folliculitis keloidalis nuchae, but reports no new clinical results.

      research Pharmacological therapeutics in androgenetic alopecia

      3 citations , May 2020 in “Journal of The Korean Medical Association”
      This review discusses treatment options for androgenetic alopecia, with a focus on the better efficacy of oral finasteride and dutasteride over topical minoxidil for male pattern hair loss, but it reports no new clinical results.