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research More About X-Linked Testicular Feminization of the Mouse as a Noninducible (is) Mutation of a Regulatory Locus: 5α-Androstan-3α-17β-Diol as the True Inducer of Kidney Alcohol Dehydrogenase and β-Glucuronidase

38 citations, May 1971 in “Clinical genetics”

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

research EtG Quantification in Hair and Different Reference Cut-Offs in Relation to Various Pathologies: A Scoping Review

12 citations, November 2022 in “Toxics”

EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.

research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes

43 citations, August 2010 in “Expert Opinion on Investigational Drugs”

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients

research Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients

March 2017 in “Fundamental & Clinical Pharmacology”

The model and estimator can predict drug exposure in kidney transplant patients well.

research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions

506 citations, January 2012 in “Molecular and Cellular Endocrinology”

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

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community Finasteride/dut. causes NAFLD,IR,diabetes,kidney dysfunction is it correct.

in Finasteride/Dutasteride 139 upvotes 1 year ago

Hair loss discussion mentions treatments like Finasteride, Dutasteride, and Minoxidil. Users share experiences, side effects, and advice on using these treatments.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 373 upvotes 1 month ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community On Fin 5 days a week and dut twice a week and still rapidly losing hair. HOW?? 9 months on fin!

in Finasteride/Dutasteride 25 upvotes 2 years ago

A user using finasteride and dutasteride to treat hair loss, but still losing hair rapidly after stopping minoxidil. Replies suggest that the user should try oral minoxidil or switch to dutasteride for better results.

community drinking topical minoxidil – extreme hair growth everywhere

in Minoxidil 396 upvotes 2 years ago

At this point. In this conversation, users discussed the risks of drinking topical minoxidil and suggested alternative treatments such as obtaining a prescription for oral minoxidil or finasteride.

community Will my liver get destroyed long term on this stack ??

in Chat 15 upvotes 10 months ago

A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.

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