September 2025 in “Archives of Dermatological Research” In this retrospective chart review, researchers found that keratinocyte carcinomas on the scalp and forehead of non-alopecic women occurred more frequently in the part line of the scalp, with basal cell carcinoma being more common than squamous cell carcinoma.
September 2024 in “Journal of the American Academy of Dermatology” In this study, DataDerm revealed that from 2016 to 2022, a majority of patients diagnosed with keratinocyte carcinoma were male, predominantly white, and commonly between 56-75 years old, with most living in urban areas and having a history of non-melanoma skin cancer.
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June 2020 in “Cells” In this study, mice lacking podoplanin in epidermal keratinocytes showed reduced tumor cell invasion and peritumoral lymphangiogenesis, suggesting that keratinocyte-expressed podoplanin contributes to advanced stages of skin tumor progression.
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March 2009 in “Molecular Carcinogenesis” This study found that Bcl-xL deficiency in mice increased apoptosis and resistance to skin tumor development, highlighting Bcl-xL's role in early skin carcinogenesis through anti-apoptotic functions.
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April 2021 in “Pharmaceuticals” This study found that curcumin encapsulated in liposomes enhanced photodynamic therapy's effectiveness against skin cancer cells while reducing toxicity to normal human keratinocytes.