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Glossary Keratin 85

protein crucial for hair structure and strength

Keratin 85, also known as KRT85, is a type of protein found in hair follicles. It plays a crucial role in the structure and strength of hair, contributing to its resilience and elasticity. Mutations in the KRT85 gene can lead to hair disorders, such as monilethrix, which is characterized by beaded or fragile hair.

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What role does keratin play in strengthening weak or thinning hair? Keratin strengthens hair by forming protective structures that prevent breakage and thinning.
Are keratin treatments good for people with alopecia, or do they only improve the hair’s appearance? Keratin treatments improve hair appearance but do not address alopecia or stimulate growth.
Is keratin in shampoos and conditioners actually absorbed by the hair, or does it just coat the surface? Keratin in shampoos mainly coats the hair rather than being absorbed.
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Research

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research 839 Spatiotemporal antagonism in mesenchymal-epithelial Signaling in sweat versus hair fate decision

April 2017 in “Journal of Investigative Dermatology”

This study identified that in mice, sweat gland development is directed by mesenchymal signals that suppress SHH-production, while in humans, this occurs through a BMP spike in embryonic development.

research 837 From genotoxic stresses to skin damage: Distinct, novel mechanisms of skin and hair damage in chemo/radiation therapy

April 2017 in “Journal of Investigative Dermatology”

This study found that down-regulation of sonic hedgehog gene expression is a critical early event in chemotherapy-induced tissue damage in hair and feather follicles.

research Integrated miRNA-mRNA analysis reveals regulatory pathways underlying the curly fleece trait in Chinese tan sheep

17 citations , May 2018 in “BMC genomics”

This study found that miR-432 inhibits KRT83 expression, revealing potential molecular mechanisms for the formation of curly fleece in Tan sheep and suggesting implications for understanding curly hair formation in humans.

research Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers

7 citations , June 2021 in “Amino acids”

This study found that protein arginine methylation levels in human hair may correlate with a cardiovascular biomarker in blood, suggesting hair sampling as a potential non-invasive method for cardiovascular risk assessment.

research Differential expression of KRT83 regulated by the transcript factor CAP1 in Chinese Tan sheep

5 citations , March 2017 in “Gene”

This study found that the transcription factor CAP1 negatively regulates KRT83 expression in Tan sheep, possibly influencing their curly hair phenotype.

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Community Join

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community Are carbohydrates needed for hair growth

26 upvotes 2 years ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

community What else is good. Besides the big 3.

in Chat 35 upvotes 1 year ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Keratin fibers vs. Gossypium Herbaceum Hair fibers

1 upvotes 2 years ago

The conversation is about comparing keratin hair fibers to Gossypium Herbaceum hair fibers for diffuse hair loss. The user prefers keratin fibers for their durability and is seeking a bulk purchase option.

community Keratin microspheres - breakthrough

14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Is keratin fusion bond good alternative to clip on hair patch for diffused thinners

4 upvotes 3 years ago

Keratin fusion bonds are discussed as an alternative to clip-on hair patches for men with diffused thinning. The conversation explores different styling options for hair loss.

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