January 2022 in “SSRN Electronic Journal” This study reports that aging in mice leads to curved hair follicles and an increase in white hairs, potentially due to changes in keratinocyte and melanocyte stem cells.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” According to this study, human scalp hair follicles containing pluripotent stem cells demonstrated the ability to differentiate into cardiac muscle cells and other cell types, suggesting potential applications in heart and nerve regeneration.
April 2017 in “Journal of dermatological science” This study reported that human hair follicles containing pluripotent stem cells can differentiate into cardiac muscle and other cells, indicating their potential for future clinical applications in heart and nerve regeneration.
419 citations
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March 2005 in “Proceedings of the National Academy of Sciences” This study demonstrated that ND-GFP stem cells from the hair-follicle bulge area can differentiate into various cell types, including neurons, suggesting their potential as a source for therapeutic applications.
387 citations
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November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.