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research Topical sulfonylurea as a novel therapy for hypertrichosis secondary to diazoxide, and potentially for other conditions with excess hair growth

5 citations , September 2015 in “Medical hypotheses”

This article suggests that a topical sulfonylurea drug may inhibit excessive hair growth caused by diazoxide without affecting its beneficial effects on beta cells, potentially offering a treatment for various forms of hypertrichosis and hirsutism.

research K channel therapeutics at the bedside

119 citations , June 2005 in “Journal of Molecular and Cellular Cardiology”

This article reviews the therapeutic potential of potassium channel openers for various conditions related to metabolic distress but does not report new clinical results; it emphasizes the need for further research.

research KATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema

18 citations , October 2020 in “Journal of Pharmacology and Experimental Therapeutics”

In isolated rat lymph vessels, this study found that ATP-sensitive potassium channel openers impair lymph contractions and reduce lymph flow, potentially contributing to peripheral edema.

research Potassium channel openers: pharmacological and clinical aspects

119 citations , October 1992 in “Fundamental & Clinical Pharmacology”

This review discusses the pharmacological properties and therapeutic potential of K+ channel opening compounds, noting their prospective use in treating cardiovascular and respiratory conditions, but reports no new results.

research K _ATP Channels and Cardiovascular Disease

144 citations , March 2013 in “Circulation Research”

This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.

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community Minoxidil’s mechanism of action on blood pressure as a potassium channel opening molecule

in Research 83 upvotes 7 months ago

Minoxidil works by opening potassium channels, leading to reduced blood pressure and potential side effects like reflex tachycardia. It is used for hair growth and affects blood pressure at high doses.

community Hairline stable but diffuse thinning with topical fin+min

in Finasteride 237 upvotes 7 months ago

The user experienced stable hairline but diffuse thinning after switching from oral finasteride to a topical solution of minoxidil and finasteride. They are concerned about the effectiveness of the topical treatment and are considering other options due to a recent decline in hair density.

community Creatine Doesn’t Cause Hair Loss: Stop the BS

137 upvotes 11 months ago

Creatine does not cause hair loss, despite many users reporting personal experiences of hair shedding. Scientific evidence shows no link between creatine and increased hair loss or hormone changes.

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