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GlossaryKeratin 2 (K2)

protein providing structural strength to skin, hair, and nails

Keratin 2 (KRT2) is a type of protein found in the outer layer of the skin, hair, and nails. It plays a crucial role in providing structural strength and resilience to these tissues, helping to protect them from damage and wear. Mutations in the KRT2 gene can lead to skin disorders such as ichthyosis bullosa of Siemens, which is characterized by blistering and scaling of the skin.

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research A Homozygous Missense Variant in K25 Underlying Overlapping Phenotype With Woolly Hair and Dental Anomalies

2 citations, August 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

A specific mutation in the K25 gene causes a rare genetic disorder with curly hair at birth and later hair loss, along with dental issues.

research Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation

32 citations, April 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Loss of keratin K2 causes skin problems and inflammation.

Physicochemical Characterization of Finasteride: PEG 6000 and Finasteride: Kollidon K25 Solid Dispersions, and Finasteride: Beta-Cyclodextrin Inclusion Complexes

research Physicochemical Characterization of Finasteride: PEG 6000 and Finasteride: Kollidon K25 Solid Dispersions, and Finasteride: Beta-Cyclodextrin Inclusion Complexes

11 citations, August 2011 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry”

Finasteride's solubility and bioavailability improved by forming solid dispersions and inclusion complexes.

research Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis

31 citations, April 2016 in “Nature communications”

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

research Preparation of Finasteride via Oxidative Elimination of 2-Iododihydrofinasteride Using Peroxydisulfates as Oxidizing Agents

1 citations, January 2017 in “Chinese Journal of Organic Chemistry”

Using K2S2O8 as an oxidizing agent in a specific condition, we can make Finasteride with 96.3% yield and 99.6% purity. This method is also good for other compounds and is environmentally friendly.

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community Looking for suggestions on vitamins

in Female 6 upvotes 1 year ago

A user is seeking affordable hair vitamins without biotin, already taking zinc and D3+K2, and has been dealing with chronic telogen effluvium since 2013. They previously used Nutrafol Vegan but found it too expensive.

community 8 months progress on min & fin

in Progress Pictures 142 upvotes 2 days ago

The user reported 8 months of hair regrowth progress using 2.5mg oral minoxidil and 0.025% topical finasteride, with no side effects. They also use Keto shampoo and vitamin D3+K2 supplements.

community Experiences with topical Finasteride (0.0125%)?

in Finasteride/Dutasteride 6 upvotes 2 weeks ago

A 23-year-old male with slight hair thinning is using ketoconazole shampoo, biotin, zinc, magnesium, D3/K2, and has just started topical finasteride (0.0125%). He plans to add minoxidil (4.5%) with 17α-estradiol and is seeking advice on the effectiveness and side effects of these treatments, as well as the use of a dermaroller.

community PSA: Check your vitamin D levels!

in Treatment 314 upvotes 2 months ago

Low vitamin D levels can negatively impact hair growth, and supplementing with vitamin D, along with treatments like finasteride and minoxidil, may help improve hair health. Quitting smoking and ensuring adequate vitamin B12 and K2 intake are also suggested to support hair regrowth.

community Oral 5mg minoxidil and 1mg finastride

in Product 3 upvotes 2 months ago

The conversation is about using 5mg oral minoxidil, 1mg oral finasteride, and Keto shampoo for hair loss, with additional supplements like Biotin, multivitamins, and Vitamin D3 with K2. Suggestions include possibly switching to 2.5mg dutasteride instead of finasteride.

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