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GlossaryIsotretinoin (Isotrex)

oral medication for severe acne unresponsive to other treatments

Isotretinoin, also known by brand names like Accutane, is a powerful oral medication primarily used to treat severe acne that hasn't responded to other treatments. It works by reducing the amount of oil released by oil glands in your skin, helping your skin renew itself more quickly. While highly effective, it can have significant side effects and is typically prescribed under strict medical supervision.

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research Retinoids: New Uses and New Synthetic Agents

January 1988 in “Inpharma (Balgowlah)”

New retinoids are effective for various skin conditions and are being developed to have fewer side effects.

research The Treatment of Acne

12 citations , September 2003 in “Current paediatrics”

Early treatment of acne is important to prevent scarring and improve appearance, using medications that can have side effects.

research Heat Enhanced Follicular Delivery of Isotretinoin to the Skin

8 citations , June 2019 in “Pharmaceutical research”

Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.

research Action of Isotretinoin in Acne Rosacea and Gram-Negative Folliculitis

175 citations , April 1982 in “Journal of The American Academy of Dermatology”

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

research Isotretinoin Treatment of Acne and Related Disorders: An Update

126 citations , October 1983 in “Journal of The American Academy of Dermatology”

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

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community Isotretinoin and Tretinoin difference

in Product 2 upvotes 10 months ago

Isotretinoin and tretinoin are different; isotretinoin can cause hair loss and has more side effects. Tretinoin may affect minoxidil absorption, and users suggest waiting before applying minoxidil.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 2 years ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community Oral min and Isotretinoin (accutane) to respond

in Chat 1 year ago

Oral minoxidil combined with isotretinoin may improve hair loss treatment effectiveness. Tretinoin is known to increase the absorption of topical minoxidil.

community Which retinoid for better min absorption?

in Product 4 upvotes 1 year ago

User is on vacation in Greece and wants to buy tretinoin or isotretinoin to improve Minoxidil absorption. They are considering isotretinoin since it is available over-the-counter in Greece but requires a prescription back home.

community Dut/Minox/Needling to Dut/Oral Minox/Tretinoin/Needling

in Minoxidil 3 upvotes 1 year ago

The user had been using Minoxidil and Dutasteride with micro-needling but experienced hair loss after switching Minoxidil brands. Their doctor prescribed oral Minoxidil and Tretinoin, but the pharmacist suggested isotretinoin might be a more cost-effective alternative.

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