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Glossary Interfollicular Epidermis

outer skin layer between hair follicles

The interfollicular epidermis is the part of the skin's outer layer that exists between hair follicles. It plays a crucial role in protecting the body from environmental damage, preventing water loss, and serving as a barrier against pathogens. This area is composed of multiple layers of cells, including keratinocytes, which are responsible for producing keratin, a protein that strengthens the skin.

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Research

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research [Development of interfollicular epidermis on the surface of collagen framework of the dermis in experimental animals].

May 1992 in “PubMed”

In this study, autotransplanted interfollicular epidermis keratinocytes in a collagen dermis framework formed follicular-like structures, but their proliferation ceased after 15-20 days.

research Experimental cutaneous Bacillus anthracis infections in hairless HRS/J mice

8 citations , January 2007 in “International journal of experimental pathology”

This study observed that hairless HRS/J mice were resistant to Bacillus anthracis infection at the skin's surface, suggesting resistance may be due to increased dermal neutrophils rather than non-functional hair follicles.

research Connective tissue sheath of hair follicle is a major source of dermal type I procollagen in human scalp

4 citations , September 2012 in “Journal of dermatological science”

The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.

Hair-Cycle-Dependent Expression of Parathyroid Hormone-Related Protein and Its Type I Receptor: Evidence for Regulation at the Anagen to Catagen Transition

research Hair-Cycle-Dependent Expression of Parathyroid Hormone-Related Protein and its Type I Receptor: Evidence for Regulation at the Anagen to Catagen Transition

52 citations , May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that overexpression of parathyroid hormone-related protein in mice resulted in 30–40% shorter hair due to premature transition into the catagen phase of the hair cycle.

research Epidermal keratinocyte stem cells: their maintenance and regulation

25 citations , December 1992 in “Seminars in cell biology”

This review discusses how epidermal Langerhan's cells and dermal cells may influence keratinocyte environments, potentially aiding in the formation of stem cell niches and cellular variety in the basal layer, without providing novel results.

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Community Join

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community How dutasteride makes hair loss impossible

in Chat 142 upvotes 1 year ago

Dutasteride is discussed as a treatment that makes hair loss impossible, with some users sharing experiences of hair regrowth and side effects. Finasteride and oral minoxidil are also mentioned as treatments, with concerns about side effects and effectiveness.

community 9 months on Finasteride and still no progress and feeling hopeless

38 upvotes 10 months ago

The user has been using finasteride, minoxidil, microneedling, PRP, and ProCell therapy for hair loss but sees no progress after nine months. They are considering switching to dutasteride and possibly a hair transplant, with suggestions to add oral minoxidil.

community Hair follicle dermal papilla exosomes

2 upvotes 1 year ago

The conversation discusses using hair follicle dermal papilla exosomes for hair loss treatment. It inquires about purchasing options for this treatment.

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Learn

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learn Follicusan

learn Trichogen® (foligain)

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