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research Approaches for estimating the clinical starting dose of new dosage forms: An example of a long-acting injectable formulation of finasteride

December 2022 in “International Journal of Pharmaceutics”

This study estimated the starting dose range for a finasteride long-acting injectable formulation in humans, suggesting that 16.80 mg may be the optimal starting dose.

research Autologous Platelet Concentrates: Their Generations, Forms, Preparation Protocols and Roles in Periodontal Regeneration

2 citations , January 2023 in “Eastern Journal Of Medicine”

This review discusses the use, efficiency, and preparation methods of autologous platelet concentrates in wound healing and periodontal regeneration, but it reports no new clinical findings.

research Platelet-Rich Plasma for the Treatment of Atopic Dermatitis: A Literature Review.

4 citations , July 2024 in “PubMed”

This study found that platelet-rich plasma therapy may improve symptoms and quality of life in adults with moderate to severe atopic dermatitis, although standardized protocols for its preparation need further study.

research Injectable Minoxidil for Hair Loss Disorders: A Systematic Review

November 2024 in “Journal of Drugs in Dermatology”

This article highlights the need for a comprehensive review of injectable minoxidil for hair loss, as existing treatments primarily focus on topical and oral forms of the medication.

Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride

research Pharmacokinetic-pharmacodynamic modeling approach for dose prediction of the optimal long-acting injectable formulation of finasteride

6 citations , March 2021 in “International Journal of Pharmaceutics”

This study reported that a subcutaneous injection formulation using PLGA microspheres to release finasteride stably achieved sustained monthly drug delivery without burst release in beagle dogs, with a dose of 16.8 mg identified as optimal for potential first-in-human trials.

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Learn

4 / 801 results

learn SCUBE3

Is SCUBE3 available in topical or injectable form, and how is it usually applied in studies? SCUBE3 is not available as a topical or injectable treatment and is not an approved medicine. In the published research it was delivered by microinjecting the recombinant protein into mouse skin and into cultured or grafted human follicles; there are no human clinical trials.

learn Thymosin Beta 4

Is Thymosin Beta 4 being explored more as a topical treatment or as a systemic (oral or injectable) approach for hair loss? Thymosin Beta 4 is primarily being explored as a topical treatment for hair loss.

learn Stem Cell Factor

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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Community Join

5 / 96 results

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

10 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for alopecia treatment. They enhance cell viability, maintain stemness, and induce hair growth without teratoma formation.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

5 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for treating alopecia and wound healing. They enhance cell viability, maintain stemness, and promote hair and tissue regeneration without teratoma formation.

community any experiences with ghk-cu for hair loss?

in Treatment 4 upvotes 3 months ago

GHK-Cu is discussed for hair loss treatment, with some users reporting positive results using a 4% topical serum, but concerns exist about the long-term safety of oral or injectable forms. The original poster also uses finasteride and plans to start dutasteride.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

11 upvotes 3 years ago

Fibrin hydrogels, when combined with stem cells, can induce hair follicle regeneration and show potential for treating alopecia. The study demonstrated successful hair growth in mice without adverse effects.

community Are topical and oral GHK-CU as effective as injectable GHK-CU, and is it worth trying it in my situation?

5 upvotes 2 months ago

The conversation discusses hair loss treatments, specifically comparing topical and injectable GHK-CU, with the user considering it after experiencing side effects from finasteride and using minoxidil. Other users suggest injectable GHK-CU for cost-effectiveness and mention using topical finasteride, dutasteride, and RU58841 for better results.

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