Search
for

    Did you mean 5AR inhibitory activity?
    Glossary5α-reductase inhibitory activity

    blocks enzyme converting testosterone to hair-loss-linked DHT

    5α-reductase inhibitory activity refers to the ability of a substance to block the action of the enzyme 5α-reductase. This enzyme converts testosterone into dihydrotestosterone (DHT), a hormone linked to hair loss and conditions like benign prostatic hyperplasia. By inhibiting 5α-reductase, these substances can help reduce DHT levels, potentially preventing hair loss and treating related conditions.

    Related Terms

    Learn

    5 / 11 results

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

    Research

    5 / 1000+ results

    Community Join

    5 / 828 results

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 11 months ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community SAFFLOWER OIL good alternative for Minoxidil?

      in Treatment  1 upvotes 4 years ago
      Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 8 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community Sanguisorba Officinalis Root Extract, and other FGF-5 inhibitors?

      in Question  4 upvotes 7 years ago
      The conversation discusses the potential of Sanguisorba Officinalis Root Extract as a treatment for hair loss by inhibiting FGF-5. The user also mentions the product évolis, which is based on this extract but is only available in the US and Australia.