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research Ingredients of Trichological Shampoos with Alleged Beneficial Effects on Hair—What Is Really Known About Their Efficacy? A Scoping Review of an Area with More Unknowns than Knowns

November 2025 in “Cosmetics”

This study found that of the many ingredients advertised in shampoos as effective against hair loss, only caffeine, adenosine, placental proteins, and melatonin have limited clinical evidence supporting their efficacy, with most claimed active ingredients lacking any trial-based validation.

research Ingredients of Trichological Shampoos with Alleged Beneficial Effects on Hair – What Is Really Known About Their Efficacy? A Scoping Review of an Area with More Unknowns than Knowns

October 2025

This study found that while many shampoo ingredients are marketed as effective against hair loss, only caffeine, adenosine, placental proteins, and melatonin have moderate clinical evidence for efficacy, and a majority of other claimed active ingredients lack clinical trial verification.

research Ingredients Present In Personal Care Products That Need Scrutiny

March 2022

Certain ingredients in personal care products, like formaldehyde, oxidative hair dyes, and sulfates, pose health risks and need careful review.

research Shampoos: Ingredients, efficacy and adverse effects

67 citations , April 2007 in “Journal der Deutschen Dermatologischen Gesellschaft”

This article reviews the development and formulation of shampoos, emphasizing their dual role as cosmetic and medicinal products, but presents no new experimental findings.

research Regulatory Mechanisms of Natural Active Ingredients and Compounds on Keratinocytes and Fibroblasts in Mitigating Skin Photoaging

10 citations , August 2024 in “Clinical Cosmetic and Investigational Dermatology”

This review reports that natural compounds show promise in slowing skin photoaging by targeting cellular pathways in keratinocytes and fibroblasts. However, comprehensive clinical studies are needed to verify their efficacy and safety.

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community New ingredients - GHK-Cu or Acetyl Tetrapeptide-3?

2 upvotes 7 months ago

GHK-Cu and Acetyl Tetrapeptide-3 are ineffective for hair regrowth according to user experiences. Effective treatments mentioned are finasteride, dutasteride, and minoxidil.

community Which Ingredient is causing Burning Red Scalp?

in Minoxidil 3 upvotes 1 year ago

The conversation is about identifying the cause of a burning red scalp from a topical hair loss formula. Retinoic acid and ethyl alcohol are suspected irritants, with retinoic acid being considered for removal.

community inactive ingredients of Sandoz Finasteride 5mg compared too Proscar and Propecia?

3 upvotes 11 years ago

The conversation discusses the differences in inactive ingredients between Sandoz 5mg Finasteride and Proscar/Propecia, questioning the purpose of certain additives like Docusate sodium. It seeks to determine if these differences affect the effectiveness of the treatment for hair loss.

community Thoughts on these ingredients for hair loss?

2 upvotes 6 months ago

A user is considering a topical hair loss treatment containing Minoxidil, Finasteride, and other ingredients. Some users suggest the doses are high and recommend starting with lower percentages.

community DIY topical finasteride ingredients

1 upvotes 9 months ago

The conversation is about creating a DIY topical finasteride solution using ethyl alcohol and propylene glycol. A user suggests using a compounding pharmacy instead.

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Learn

7 / 800 results

learn flower extract (capixyl ingredient)

learn Biotin

Biotinyl-GHK: a miracle ingredient against hair loss? Biotinyl-GHK (biotinoyl tripeptide-1) is a cosmetic ingredient, not an approved hair-loss medicine; the published studies test it only inside multi-ingredient complexes such as Procapil, so no result can be attributed to the peptide itself.

learn Redensyl

Cosmetic ingredient blend sold for thinning hair

What does Redensyl do that other natural ingredients don't? Redensyl's maker says it acts on follicle stem cells; the only human data are small supplier studies, not independent trials.

learn Coconut Oil

Can I mix coconut oil with other ingredients to boost its effect? Some people mix coconut oil with honey, aloe or diluted essential oils; there is little evidence these mixtures work better, and any added ingredient can cause irritation or allergy - patch-test first.

learn retinol

Can retinol help enhance the absorption of ingredients like minoxidil or peptides? No human study has measured whether retinol increases scalp absorption of minoxidil or peptides. Retinoids thicken rather than thin the epidermis, and they can irritate skin and need caution in pregnancy.

learn Adenosine

Molecule the body uses for energy, used as a cosmetic hair-lotion ingredient

Adenosine: How natural is this ingredient and how does it act on the scalp? Adenosine occurs naturally in the body, but the lotion ingredient is made synthetically. Small trials found it increased the share of thick hairs.

learn Stemoxydine

Cosmetic ingredient made by L'Oréal

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