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research Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells

3 citations , August 2014 in “Cellular reprogramming”

This study found that multipotent neural crest stem cells from hair follicles require a full set of reprogramming factors for induced pluripotent stem cell induction, similar to fibroblasts.

research Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells

10 citations , January 2014 in “BioMed research international”

In this study, dermal papilla cells from rat vibrissae showed potential for treating CNS injuries by secreting neurotrophic factors and promoting neuronal differentiation more effectively than bone marrow mesenchymal stem cells.

research Highly Efficient Neural Differentiation of CD34-Positive Hair-Follicle-Associated Pluripotent Stem Cells Induced by Retinoic Acid and Serum-Free Medium

4 citations , January 2016 in “Methods in molecular biology”

This chapter reviews the methodology for isolating and differentiating CD34+ HAP stem cells into neural cells, but provides no new research results.

research Culture of pyramidal neural precursors, neural stem cells, and fibroblasts on various biomaterials

3 citations , September 2018 in “Journal of Biomaterials Science, Polymer Edition”

This study found that pyramidal neural precursors best grew neurites on matrigel, while neural stem cells differentiated directionally on aligned fibrin, suggesting the importance of biomaterial selection for cell culture.

research Stem Cells in Regenerative Medicine: A Journey from Adult Stem Cells to Induced Pluripotent Cells

3 citations , August 2025 in “International Journal of Molecular Sciences”

This review discusses various types of stem cells used in regenerative medicine, including adult stem cells and induced pluripotent stem cells (iPSCs), and evaluates them based on their embryonic tissue origins to explore new therapeutic approaches.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Apple stem cell

learn Grape stem cells

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community Average r/bald user complaining

401 upvotes 9 months ago

Hair loss treatments like Minoxidil, finasteride, and RU58841, focusing on their effectiveness and side effects. It also highlights the disparity in medical research funding between hair loss and conditions like endometriosis.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 4 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

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