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research Correlation between increased total serum IgE levels and clinical features in alopecia areata patients

1 citations , June 2025 in “Frontiers in Immunology”

This study found that total serum IgE levels were elevated in patients with alopecia areata compared to controls, suggesting a possible involvement of IgE and Th2 cytokines in its pathogenesis.

research Alopecia areata in childhood

March 2014 in “Journal of the American Academy of Dermatology”

Alopecia areata is relatively common in children, has a variable course, and shows different responses to treatment; thyroid testing is recommended for those affected.

Diffuse Alopecia Areata Is Associated With Intense Inflammatory Infiltration and CD8+ T Cells in Hair Loss Regions and an Increase in Serum IgE Level

research Diffuse alopecia areata is associated with intense inflammatory infiltration and CD8+ T cells in hair loss regions and an increase in serum IgE level

24 citations , January 2012 in “Indian Journal of Dermatology, Venereology and Leprology”

This study suggests that hypersensitivity and increased serum IgE levels might contribute to the pathogenesis of diffuse alopecia areata through intense local inflammatory infiltration.

Upadacitinib for the Treatment of Systemic Immune Co-Morbidity in One Case: Alopecia Areata, Vitiligo, Ankylosing Spondylitis, and Allergic Rhinitis-Asthma – Multifaceted Control

research Upadacitinib for the Treatment of Systemic Immune Co-Morbidity in One Case: Alopecia Areata, Vitiligo, Ankylosing Spondylitis, and Allergic Rhinitis-Asthma – Multifaceted Control

March 2026 in “Clinical Cosmetic and Investigational Dermatology”

In this case study, treatment with the selective JAK1 inhibitor upadacitinib significantly improved symptoms in a patient with refractory alopecia areata, vitiligo, ankylosing spondylitis, and allergic asthma-nasal syndrome, though a transient liver function abnormality was noted.

research Successful induction of oral tolerance in Netherton syndrome

11 citations , October 2011 in “Allergologia et immunopathologia”

A girl with Netherton syndrome was able to eat wheat without allergies after a special treatment.

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community 13 Years Finasteride, Switched to Dutasteride - 25% increase in Total Testosterone (expected) but 150% increase in Free Testosterone?

27 upvotes 11 months ago

After switching from finasteride to dutasteride, the user experienced a 25% increase in total testosterone and a 150% increase in free testosterone, with side effects like brain fog and nipple tingling. The user plans to consult a lab for accuracy and adjust the dutasteride dosage to manage side effects.

community Finasteride Doubled my Total & Free Test but also my Estradiol - 8 months in

in Chat 32 upvotes 1 month ago

A 22-year-old male experienced increased testosterone and estradiol levels after 8 months on finasteride, leading to softer erections and reduced arousal. Suggestions included reducing finasteride dosage, using supplements like L-arginine, L-citrulline, zinc, and possibly tadalafil to improve symptoms.

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