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GlossaryImmunomodulators

substances that regulate or normalize the immune system

Immunomodulators are substances that help regulate or normalize the immune system. They can either boost the immune response to fight infections and diseases or suppress it to prevent overactivity, which can lead to conditions like autoimmune diseases. For example, in the context of alopecia, immunomodulators might be used to reduce the immune system's attack on hair follicles.

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learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

Research

5 / 1000+ results

$Fibroblasts: Immunomodulatory Factors in Refractory Diabetic Wound Healing$

research Fibroblasts: Immunomodulatory Factors in Refractory Diabetic Wound Healing

20 citations, August 2022 in “Frontiers in Immunology”

Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.

research Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome

271 citations, May 2019 in “Cells”

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

research Functional Enhancement Strategies for Immunomodulation of Mesenchymal Stem Cells and Their Therapeutic Application

53 citations, September 2020 in “Stem Cell Research & Therapy”

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration

220 citations, March 2020 in “Advanced functional materials”

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

research Activation of TLR3 Enhances Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells

3 citations, December 2016 in “Springer eBooks”

Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.

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Community Join

3 / 3 results

community Fin/dut ONLY users, this has been my experience so far

in Finasteride/Dutasteride 97 upvotes 1 week ago

The user has been using finasteride for hair loss since January 2023, initially seeing improvement but now experiencing increased thinning. They are considering other factors like thyroid and insulin resistance and are seeking advice from long-term finasteride users, while some suggest trying dutasteride, minoxidil, or consulting a dermatologist for further evaluation.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 2 years ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Anyone else taking Litfulo (ritlecitinib) to treat their alopecia?

in Treatment 5 upvotes 1 year ago

A user diagnosed with Alopecia Areata started using Litfulo (ritlecitinib), kenalog shots, and mometasone furoate 0.1%. They shaved their head and are seeking others' experiences with Litfulo.