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Glossary Immunomodulators

substances that regulate or normalize the immune system

Immunomodulators are substances that help regulate or normalize the immune system. They can either boost the immune response to fight infections and diseases or suppress it to prevent overactivity, which can lead to conditions like autoimmune diseases. For example, in the context of alopecia, immunomodulators might be used to reduce the immune system's attack on hair follicles.

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$Fibroblasts: Immunomodulatory Factors in Refractory Diabetic Wound Healing$

research Fibroblasts: Immunomodulatory factors in refractory diabetic wound healing

20 citations , August 2022 in “Frontiers in Immunology”

This review discusses the role of fibroblasts in treating diabetic complications and wound healing, highlighting their potential as immunomodulatory factors but provides no new clinical results.

research ‘Neurotrophology’ of the hair follicle: neurotrophins act as auto‐ and paracrine growth factors and immunomodulators

August 2006 in “Experimental dermatology”

This study found that nerve growth factor signaling in organ-cultured human hair follicles inhibits hair growth by inducing apoptosis-driven hair follicle regression.

Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment

research Exfoliative cutaneous lupus erythematosus in German shorthaired pointer dogs: disease development, progression and evaluation of three immunomodulatory drugs (ciclosporin, hydroxychloroquine, and adalimumab) in a controlled environment

21 citations , April 2010 in “Veterinary Dermatology”

This study documented the progression of exfoliative cutaneous lupus erythematosus in German shorthaired pointers and found generally poor responses to therapies, including immunomodulatory drugs and a TNF-α inhibitor.

research The protective role of the immunomodulator AS101 against chemotherapy-induced alopecia studies on human and animal models

85 citations , January 1996 in “International Journal of Cancer”

In this study, AS101 combined with chemotherapy significantly reduced the severity of chemotherapy-induced alopecia in non-small-cell-lung-cancer patients and may involve immune mechanisms related to IL-1 and PGE2.

research 3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects

13 citations , August 2024 in “iScience”

This study found that 3D spheroid culture reprogrammed mesenchymal stem cells into a uniform immunosuppressive phenotype, suggesting potential therapeutic applications for inflammatory diseases like psoriasis.

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Community Join

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community Fin/dut ONLY users, this has been my experience so far

in Finasteride/Dutasteride 97 upvotes 1 year ago

The user has been using finasteride for hair loss since January 2023, initially seeing improvement but now experiencing increased thinning. They are considering other factors like thyroid and insulin resistance and are seeking advice from long-term finasteride users, while some suggest trying dutasteride, minoxidil, or consulting a dermatologist for further evaluation.

community Making your own RT1640 in China

4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

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learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

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