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      Understanding the Intricate Pathophysiology of Psoriasis and Related Skin Disorders

      research Understanding the Intricate Pathophysiology of Psoriasis and Related Skin Disorders

      January 2025 in “International Journal of Molecular Sciences”
      This narrative review explored the complex interconnections between psoriasis and other dermatological conditions like vitiligo, alopecia areata, and atopic dermatitis, highlighting shared immune dysfunctions that complicate diagnosis and treatment, with implications for research and holistic patient care.

      research The regenerative potential of skin and the immune system

      41 citations , July 2019 in “Clinical Cosmetic and Investigational Dermatology”
      This paper explores the complex immune processes and cellular diversity that enable the skin to heal and resist invasion, and highlights its potential as a model for studying regeneration.

      research Epidermal stem cells: skin surveillance and clinical perspective

      19 citations , August 2024 in “Journal of Translational Medicine”
      This review explores recent advancements in understanding how various physiological and psychological factors, such as stress and aging, influence epidermal stem cell populations, highlighting their importance in immune-related skin disorders and potential for clinical applications.
      Pregnancy and Skin: Changes and Dermatoses

      research Pregnancy and Skin

      26 citations , June 2012 in “The Journal of Obstetrics and Gynecology of India”
      This review discusses various skin changes during pregnancy, noting that while most are benign and resolve after childbirth, some may require careful medical management for the safety of the mother and fetus; it reports no new results.
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    Community Join

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      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

       63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community My Theory Of Androgenic Alopecia

       16 upvotes 10 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

       413 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community He used Dutasteride for 20 years. Interview

       113 upvotes 1 year ago
      Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.
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    Learn

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      learn Vitamin D

      vitamin you should probably be taking for general health might also help your hair a little

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties
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    Experts

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    Clinics

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