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research Immunological Properties of Atopic Dermatitis-Associated Alopecia Areata

57 citations , March 2021 in “International Journal of Molecular Sciences”

This study found that type 2 immunity may play a role in the development of alopecia areata in patients with extrinsic atopic dermatitis, indicating different immunological states compared to non-atopic patients.

research Dupilumab Alters Both the Bacterial and Fungal Skin Microbiomes of Patients with Atopic Dermatitis

8 citations , January 2024 in “Microorganisms”

This study found that administering dupilumab to patients with moderate-to-severe atopic dermatitis over 12 weeks altered both fungal and bacterial skin microbiomes, increasing microbial diversity and decreasing colonization by Malassezia and Staphylococcus aureus at lesion sites.

research 177 Chronic graft-versus-host disease exhibits distinct Th1-skewing and barrier abnormalities in the skin

April 2023 in “Journal of Investigative Dermatology”

In this study, researchers developed a mouse model of scarring alopecia and observed significant reductions in CD200R expression in affected skin, potentially linking this signaling pathway to immune attacks on hair follicles and suggesting new treatment targets for scarring hair loss.

research Successful Treatment of Coexisting Alopecia Areata and Bullous Pemphigoid With Dupilumab: A Case Report

August 2025 in “JEADV Clinical Practice”

In this case report, researchers documented a 71-year-old woman with both alopecia areata and bullous pemphigoid who showed significant improvement using dupilumab after other treatments failed, highlighting its potential for autoimmune diseases with overlapping inflammatory mechanisms.

Type 2-Mediated Oxidative Reprogramming Promotes Macrophage Transition into Repair Mode for Wound Healing

research 1497 Type 2-mediated oxidative reprogramming promotes the transition of macrophages into repair mode and is required for wound healing

April 2023 in “Journal of Investigative Dermatology”

This study identified a new role for IL-4Ra-induced oxidative metabolism in wound macrophages, essential for balancing inflammatory response and promoting pro-fibrotic repair, suggesting a target for fibrosis prevention.

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Learn

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learn Thymosin Beta 4

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community Il PP405 è molto promettente ma non è l'unico in grado di liberarci dalla iattura

3 upvotes 1 year ago

PP405 shows promise in hair loss treatment, but stem cell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stem cell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.

community Today I received my first Batch Follicopeptide

in Treatment 139 upvotes 7 months ago

A user purchased an expensive hair loss treatment called Follicopeptide, which many others in the conversation believe to be a scam, suggesting instead the use of proven treatments like minoxidil and finasteride. Some users report positive effects from Follicopeptide, but skepticism remains high due to lack of transparency about its ingredients and the company's credibility.

community Why I believe PFS is not a "real" condition (and what I believe it is instead)

14 upvotes 3 years ago

The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.

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Clinics

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