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GlossaryInterleukin-12 (IL12)

protein that activates immune cells to fight infections

Interleukin-12 (IL-12) is a protein produced by certain immune cells that plays a crucial role in regulating the body's immune response. It helps activate natural killer (NK) cells and T cells, which are essential for fighting infections and cancer. IL-12 is also involved in the inflammatory response and can influence the development of autoimmune diseases.

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research Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells

9 citations, April 2019 in “Biomolecules & Therapeutics”

Udenafil may help hair grow by activating certain stem cells.

research Molecular Genetic Dissection of ILVEN Leads to Successful Targeted Therapy

September 2019 in “Journal of Investigative Dermatology”

Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.

Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?

research Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?

June 2022 in “Frontiers in Immunology”

Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.

research Androgens and Acne: Perspectives on Clascoterone, the First Topical Androgen Receptor Antagonist

9 citations, April 2021 in “Expert opinion on pharmacotherapy”

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

research Dermatologic Toxicities Associated with Chronic Gamma-Secretase Inhibitor Treatment for Desmoid Tumor

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.

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