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GlossaryInterleukin-12 (IL12)

protein that activates immune cells to fight infections

Interleukin-12 (IL-12) is a protein produced by certain immune cells that plays a crucial role in regulating the body's immune response. It helps activate natural killer (NK) cells and T cells, which are essential for fighting infections and cancer. IL-12 is also involved in the inflammatory response and can influence the development of autoimmune diseases.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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research Discrimination of Dysplastic Nevi from Common Melanocytic Nevi by Cellular and Molecular Criteria

41 citations , July 2016 in “Journal of Investigative Dermatology”

Dysplastic nevi have unique gene expressions, making them distinct from common melanocytic nevi.

research Case Report: Treatment-Resistant Pityriasis Rubra Pilaris Achieving Remission with Ustekinumab

25 citations , March 2021 in “Australasian Journal of Dermatology”

Ustekinumab successfully treated a man's resistant skin condition when other treatments failed.

research Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells

9 citations , April 2019 in “Biomolecules & Therapeutics”

Udenafil may help hair grow by activating certain stem cells.

research Molecular Genetic Dissection of ILVEN Leads to Successful Targeted Therapy

September 2019 in “Journal of Investigative Dermatology”

Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.

Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?

research Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?

June 2022 in “Frontiers in Immunology”

Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.

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