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GlossaryIfosfamide

chemotherapy drug that interferes with cancer cell DNA

Ifosfamide is a chemotherapy drug used to treat various types of cancer, including lymphomas and sarcomas. It works by interfering with the DNA of cancer cells, preventing them from growing and dividing. However, it can also cause side effects like hair loss (alopecia) and damage to the bladder and kidneys, so it is often administered with protective agents to mitigate these risks.

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research Protection from Ifosfamide-Induced Alopecia by Topical Thiols in Young Rats

3 citations, January 1990 in “Cancer chemotherapy and pharmacology”

Topical thiols may prevent hair loss caused by certain chemotherapy drugs.

research Hypertrichosis Lanuginosa Acquisita Following Cytotoxic Chemotherapy

4 citations, January 1992 in “Clinical Oncology”

Some cancer treatments can cause abnormal fine hair growth.

research Resolution of Plantar Hyperkeratosis of Pachyonychia Congenita During Chemotherapy for Ewing Sarcoma

2 citations, August 2013 in “British Journal of Dermatology”

Chemotherapy improved a girl's painful foot condition linked to pachyonychia congenita.

research TICE Salvage Chemotherapy Treats Germ-Cell Tumors Effectively

April 2007 in “Nature Clinical Practice Urology”

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

research Cytostatics and Immunosuppressive Drugs: Toxicities and Management

January 1989 in “Side effects of drugs annual”

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

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