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Melatonin Alleviates Oxygen-Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2/ROS/NLRP3 Pathway

research Melatonin Alleviates Oxygen-Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2/ROS/NLRP3 Pathway

5 citations , November 2022 in “Molecular Neurobiology”

Melatonin may protect inner ear cells from damage by reducing cell death and oxidative stress, potentially treating sudden hearing loss.

research Role of Ciclosporin in Steroid-Responsive Sudden Sensorineural Hearing Loss

8 citations , January 2005 in “Acta Oto-Laryngologica”

Ciclosporin might be a good alternative treatment for certain hearing loss that responds to steroids.

research Fibrinogen and LDL Apheresis in Treatment of Sudden Hearing Loss: A Randomised Multicentre Trial

177 citations , December 2002 in “The Lancet”

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

research Audiological Evaluation in Autoimmune Skin Diseases: A Clinical Study of 124 Patients

April 2015 in “Journal of Evolution of Medical and Dental Sciences”

People with autoimmune skin diseases often have hearing problems and should get their hearing checked early.

research The Role of Platelet-Rich Plasma in Biomedicine: A Comprehensive Overview

26 citations , January 2025 in “iScience”

PRP helps tissue repair but lacks standard preparation methods.

View more "idiopathic sudden sensorineural hearing loss" in research →

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community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

in Minoxidil 78 upvotes 2 years ago

A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

community I wish I were a man so bad. Life is cruel

in Female 219 upvotes 3 weeks ago

A woman with androgenetic alopecia uses Dutasteride and Bicalutamide but feels devastated due to increased sensitivity to DHT. She considers wigs, Minoxidil, and seeks advice on options like spironolactone, hair transplants, and therapy.

community It’s over. NOTHING has worked.

in Chat 95 upvotes 3 years ago

A user who has been trying various treatments for hair loss for four years, with no success. Suggestions include use of minoxidil, finasteride, RU58841, microneedling, supplements and multivitamins, lifestyle changes, scalp biopsy, and SMP.

community In God We Trust, Topical Fin/Min with existing ADHD issues

in Chat 19 upvotes 1 year ago

A 27-year-old male with ADHD is experiencing hair thinning and is starting a treatment with topical finasteride (0.025%) and minoxidil (5%). He is addressing high prolactin levels and low vitamin D, while managing side effects from ADHD medication.

community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

in Update 34 upvotes 6 years ago

The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.