Role of Ciclosporin in Steroid-Responsive Sudden Sensorineural Hearing Loss

The document describes a case where a 39-year-old male with idiopathic sudden sensorineural hearing loss (SNHL), which had previously responded to corticosteroids, was treated with ciclosporin after experiencing a relapse during corticosteroid tapering. Ciclosporin was used for 18 months, leading to the successful discontinuation of corticosteroids and control of SNHL symptoms, with remission confirmed by pure-tone audiometry. The document suggests that ciclosporin may be an effective alternative to long-term corticosteroid or cyclophosphamide therapy for steroid-responsive SNHL, but notes the absence of randomized control trials to confirm its efficacy for this condition.