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This study found that thyroid-stimulating hormone receptors are functionally expressed in various skin cells, implying potential physiological and pathological roles in skin, especially in conditions like autoimmune diseases.

HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.

This study observed that levothyroxine therapy in men with autoimmune hypothyroidism was less effective at reducing thyroid antibodies and hormone disruptions in those with early-onset androgenetic alopecia compared to those without hair loss.

Human hair follicles have their own thyroid hormone system.

This study found that normal human epidermis expresses TSH and may be an indirect target of TSH signaling, with expression regulated by endocrine controls of the hypothalamic-pituitary-thyroid axis.