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GlossaryHypothalamic-Pituitary-Adrenal Axis

regulates stress response through hormone release from brain and adrenal glands

The Hypothalamic-Pituitary-Adrenal (HPA) Axis is a complex network involving the hypothalamus, pituitary gland, and adrenal glands, which work together to regulate the body's response to stress. When you encounter stress, the hypothalamus releases corticotropin-releasing hormone (CRH), prompting the pituitary gland to secrete adrenocorticotropic hormone (ACTH), which in turn stimulates the adrenal glands to produce cortisol, a key stress hormone. This system plays a crucial role in maintaining homeostasis and can impact various bodily functions, including immune response and metabolism.

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research Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives

98 citations, July 2014 in “Trends in Molecular Medicine”

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

research PSAT327 Can Cannabis Use Lead to Central Hypothyroidism

November 2022 in “Journal of the Endocrine Society”

Marijuana use may be linked to lower TSH levels, but the exact cause is unclear.

research Endocrine Disorders and Infertility

1 citations, March 2011 in “Infertility”

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

research Thyroid Hormone Action on Skin

24 citations, July 2011 in “PubMed”

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

research Epidermal Renewal After Treatment of Primary Canine Hypothyroidism Using Levothyroxine

January 2021 in “Acta Scientiae Veterinariae”

Levothyroxine effectively treated a dog's skin and hair problems caused by hypothyroidism.

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community How I started reversing Male Pattern Baldness naturally ?

surkut in Question 6 upvotes 7 years ago

The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

community Why does finasteride stop working?

Extension-Tip-6536 in Finasteride/Dutasteride 26 upvotes 3 months ago

Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

community Possible "Cure" For Pos Finasteride Syndrome

mylon147 in Chat 6 upvotes 4 years ago

A user reported full recovery from Post Finasteride Syndrome after 6 months of HCG treatment. They used 250IU of HCG three times a week.

community Ru, Stemoxydine or Alfatradiol? What has your experience been with any of these 3?

RChopaa in Treatment 3 upvotes 1 year ago

The user is seeking advice on which treatment to add to their current regimen for male pattern baldness. They have previously tried Dutasteride, Nizoral, and oral Minoxidil, but experienced continued hair loss. They are specifically asking for experiences with RU58841, Stemoxydine, or Alfatradiol.

community Pyrilutamide: Increased libido. Anyone else experienced something similar with either RU or Pyri?

Number_Worried00 in Product 18 upvotes 2 years ago

An increase in libido associated with the use of Pyri, and a discussion about how it may be working comparably to other hair loss treatments such as RU58841, Finasteride and Minoxidil.

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