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GlossaryHypothalamic-Pituitary-Adrenal Axis

regulates stress response through hormone release from brain and adrenal glands

The Hypothalamic-Pituitary-Adrenal (HPA) Axis is a complex network involving the hypothalamus, pituitary gland, and adrenal glands, which work together to regulate the body's response to stress. When you encounter stress, the hypothalamus releases corticotropin-releasing hormone (CRH), prompting the pituitary gland to secrete adrenocorticotropic hormone (ACTH), which in turn stimulates the adrenal glands to produce cortisol, a key stress hormone. This system plays a crucial role in maintaining homeostasis and can impact various bodily functions, including immune response and metabolism.

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Preponderance of Serum and Intra-Hepatic 5α-Dihydrotestosterone in Males with Hepatocellular Carcinoma Despite Low Circulating Androgen Levels

research Preponderance of Serum and Intra-Hepatic 5α-Dihydrotestosterone in Males with Hepatocellular Carcinoma Despite Low Circulating Androgen Levels

8 citations, January 1986 in “Journal of hepatology”

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

research Irregular Menstruation, Acne, Hirsutism, and the Possibility of PCOS

July 2022 in “International journal of medical science and clinical invention”

Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.

research The First Visit: Consultation and Workup Before Sperm Banking

October 2017 in “Springer eBooks”

A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.

research Foreword

June 2007 in “Endocrinology and Metabolism Clinics of North America”

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

research Ovarian Hormones and Adrenal Androgens During a Woman's Life Span

24 citations, September 2001 in “Journal of The American Academy of Dermatology”

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

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community Mechanism of action of alfatradiol (17 alpha estradiol)

in Research/Science 6 upvotes 9 months ago

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

community Ru, Stemoxydine or Alfatradiol? What has your experience been with any of these 3?

in Treatment 3 upvotes 1 year ago

The user is seeking advice on which treatment to add to their current regimen for male pattern baldness. They have previously tried Dutasteride, Nizoral, and oral Minoxidil, but experienced continued hair loss. They are specifically asking for experiences with RU58841, Stemoxydine, or Alfatradiol.

community Pyrilutamide: Increased libido. Anyone else experienced something similar with either RU or Pyri?

in Product 17 upvotes 2 years ago

An increase in libido associated with the use of Pyri, and a discussion about how it may be working comparably to other hair loss treatments such as RU58841, Finasteride and Minoxidil.

community Anyone remember Breezula, the promising hairloss drug that was perpetually 3 years away? Well, it's available right now as an acme treatment. Can we just directly apply to the scalp?

in Treatment 41 upvotes 3 years ago

The conversation discusses the availability of Breezula, a drug for hair loss, now being sold as an acne treatment, and whether it can be applied to the scalp. Users express skepticism about new hair loss treatments and suggest waiting for FDA approval.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 3 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

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