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      1 citations , April 2004 in “Cancer”
      This study describes that 65% of patients receiving imatinib mesylate in a patient assistance program experienced skin hypopigmentation, primarily in ethnically Chinese individuals, suggesting variability across populations.

      research On the etiology of vitiligo and gray hair

      303 citations , August 1971 in “The American Journal of Medicine”
      This report suggests that in vitiligo, melanocytes may be destroyed by the same factors necessary for melanin production, contributing to the skin's depigmentation.

      research Acquired localized hypertrichosis.

      5 citations , March 1981 in “PubMed”
      This case report details a 2-year-old girl who developed hypertrichosis on areas of her skin affected by multiple insect bites and subsequent scratching, resulting in unusual hair growth.
      Role of Metformin in Acanthosis Nigricans

      research Role of Metformin in Acanthosis Nigricans

      January 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences”
      This study suggests that metformin's ability to enhance insulin sensitivity may improve acanthosis nigricans by addressing the underlying insulin resistance.