This study describes that 65% of patients receiving imatinib mesylate in a patient assistance program experienced skin hypopigmentation, primarily in ethnically Chinese individuals, suggesting variability across populations.
303 citations
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August 1971 in “The American Journal of Medicine”
This report suggests that in vitiligo, melanocytes may be destroyed by the same factors necessary for melanin production, contributing to the skin's depigmentation.
This case report details a 2-year-old girl who developed hypertrichosis on areas of her skin affected by multiple insect bites and subsequent scratching, resulting in unusual hair growth.
September 2024 in “Journal of the American Academy of Dermatology”
In this case report, a 53-year-old woman with Little-Graham-Piccardi-Lassueur-Syndrome responded well to a treatment regimen of hydroxychloroquine, methotrexate, and other therapies, effectively halting the progression of this rare dermatosis characterized by alopecia and hyperkeratotic eruptions.
January 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences”
This study suggests that metformin's ability to enhance insulin sensitivity may improve acanthosis nigricans by addressing the underlying insulin resistance.