November 2003 in “Aap Grand Rounds” This study found that a combination of low-dose flutamide and metformin therapy may reverse insulin resistance and reduce fat mass in nonobese adolescents with PCOS.
August 1996 in “Journal of Pediatric and Adolescent Gynecology” This article discusses the various manifestations and diagnostic challenges of polycystic ovarian syndrome and reviews its associated symptoms and clinical heterogeneity but reports no new clinical findings.
28 citations
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July 2017 in “Journal of Endocrinological Investigation” This study suggests that early onset androgenetic alopecia in men may indicate a male PCOS equivalent, possibly leading to higher risks of metabolic and cardiovascular disorders later in life.
August 2023 in “Revista Contemporânea” This review examines the relationship between fetal metabolic programming and the development of polycystic ovary syndrome, highlighting maternal and environmental factors but reports no new experimental results.
60 citations
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June 1997 in “Baillière's clinical obstetrics and gynaecology” This article reviews the potential mechanisms underlying polycystic ovary syndrome, emphasizing insulin resistance and hormone dysregulation, and reports no new research findings.