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GlossaryHydroxyurea (Hydroxycarbamide)

medication that inhibits DNA synthesis to treat cancer and blood disorders

Hydroxyurea, also known as hydroxycarbamide, is a medication primarily used to treat certain types of cancer, such as chronic myelogenous leukemia, and blood disorders like sickle cell anemia. It works by inhibiting DNA synthesis, which helps to slow the growth of cancer cells and reduce the frequency of painful sickle cell crises.

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Hydrochlorothiazide/Indometacin: Lupus Erythematosus in a 73-Year-Old Woman After Hydroxycarbamide Treatment for Essential Thrombocythemia

research Hydrochlorothiazide/Indometacin: Lupus Erythematosus in a 73-Year-Old Woman After Hydroxycarbamide Treatment for Essential Thrombocythemia

October 2009 in “Reactions Weekly”

A woman developed lupus after taking hydroxyurea for two years.

research Cutaneous Drug Reaction Case Reports

January 2003 in “American Journal of Clinical Dermatology”

Various drugs caused different skin reactions, including allergic and inflammatory responses.

research Essential Thrombocythemia: The Dermatologic Point of View

22 citations , September 2015 in “Clinical lymphoma myeloma & leukemia/Clinical lymphoma, myeloma and leukemia”

Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.

research Pathobiology of Chemotherapy-Induced Hair Loss

218 citations , January 2013 in “The Lancet Oncology”

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

research Drug-Induced Male Infertility: A Real-World Study Using FAERS and EudraVigilance Databases

January 2026 in “Frontiers in Pharmacology”

Certain drugs can cause male infertility, so fertility counseling and sperm preservation are advised.

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