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research An ROS‐Scavenging Treg‐Recruiting Hydrogel Patch for Diabetic Wound Healing

February 2024 in “Advanced Functional Materials”

This study reported that a newly developed hydrogel patch, designed to recruit regulatory T cells through ROS-triggered release of CCL22, improved wound healing and hair follicle regeneration in a diabetic mouse model by scavenging ROS, thereby protecting Tregs and suppressing Th17 cells.

research Dual-continuous microneedle patch integrating transdermal delivery of pH-sensitive licorzinc MOFs and Zn2+ hydrogel sensors for treating alopecia areata

22 citations , September 2024 in “Chemical Engineering Journal”

A new microneedle patch effectively and safely treats alopecia areata.

research In-vitro and In-vivo Characterization of Bio-Patch to Hydrogel on Skin Wounds for Efficient Scarless Wound Healing

January 2024 in “Journal of chemical health risks”

In this study, a multifunctional aloin-arginine-alginate bio-patch was developed, which transforms into a hydrogel to accelerate wound healing and offers antibacterial and anti-inflammatory benefits, making it promising for use in cutaneous regeneration.

research ControlledRelease of Minoxidil through Hydrogel Cross-Linkingto Treat Androgenetic Alopecia

June 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

This study found that a novel bioengineered microneedle patch successfully delivered minoxidil to induce hair growth in a mouse model, suggesting a promising approach to improve treatment for androgenetic alopecia.

research Controlled Release of Minoxidil through Hydrogel Cross-Linking to Treat Androgenetic Alopecia

June 2025 in “ACS Biomaterials Science & Engineering”

In this study, researchers developed a new microneedle patch delivery system for minoxidil, which enhanced its controlled release and improved hair growth in mice, potentially offering better treatment outcomes for androgenetic alopecia.

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Community Join

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community Hair-loss hope: Natural sugar stimulates significant regrowth

in Research/Science 7 upvotes 2 years ago

A naturally occurring sugar, 2-deoxy-D-ribose, in a hydrogel form, shows promise for hair regrowth similar to minoxidil in rats. The user plans to synthesize it for topical application, seeking input from others.

community Does anyone know the chemical formula for pelage pp405?

15 upvotes 1 year ago

The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

community Just received my 2 Deoxy D Ribose wish me luck🫡

245 upvotes 2 years ago

A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

community Fighting Hair loss AND Grey Hair

18 upvotes 4 years ago

The user is treating hair loss with topical Minoxidil, Finasteride, RU58841, microneedling, and Ketoconazole. For grey hair, they use L-Cysteine, L-Methionine, and PABA, and have noticed some re-pigmentation.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

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