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GlossaryHydralazine

medication that lowers blood pressure by relaxing blood vessels

Hydralazine is a medication primarily used to treat high blood pressure by relaxing the blood vessels, allowing blood to flow more easily. It can also be used off-label to manage heart failure and certain other cardiovascular conditions.

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Increased Levels of Prostaglandin-Like Material in Canine Blood During Arterial Hypotension Produced by Hydralazine, Dihydralazine, and Minoxidil

research Increased Levels of Prostaglandin-Like Material in Canine Blood During Arterial Hypotension Produced by Hydralazine, Dihydralazine, and Minoxidil

35 citations , December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology”

These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.

research Cryptococcoid Sweet Syndrome: A Case Report and Literature Review

February 2024 in “International Journal of Dermatology”

Cryptococcoid Sweet syndrome can be linked to hydralazine use and multiple autoantibodies, requiring high clinical suspicion and more research.

research A Case of Widespread Actinic Granuloma with Associated Drug-Induced Lupus Erythematosus

1 citations , April 2016 in “Journal of The American Academy of Dermatology”

A man developed a rare skin condition and drug-induced lupus, highlighting the need for biopsy in diagnosing skin issues caused by sunlight.

research Increased Plasma Renin by Vasodilators Promotes the Progression of Abdominal Aortic Aneurysm

1 citations , June 2023 in “Frontiers in Pharmacology”

Vasodilators may worsen abdominal aortic aneurysm.

Characterization of a Partial cDNA for Lysyl Hydroxylase from Human Skin Fibroblasts; Lysyl Hydroxylase mRNAs Are Regulated Differently by Minoxidil Derivatives and Hydralazine

research Characterization of a Partial cDNA for Lysyl Hydroxylase from Human Skin Fibroblasts; Lysyl Hydroxylase mRNAs Are Regulated Differently by Minoxidil Derivatives and Hydralazine

46 citations , December 1992 in “Journal of Investigative Dermatology”

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

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community So does oral minoxidil age your skin or not

in Minoxidil 44 upvotes 1 year ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.