Search

for
Search:

Research

5 / 1000+ results

Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression

research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression

128 citations , March 2006 in “American Journal of Pathology”

The study found that prolactin expressed in human scalp hair follicles acts as an autocrine modulator, inhibiting hair growth and promoting hair follicle regression, which may contribute to hair loss in hyper-prolactinemia patients.

research Three-dimensional architecture of macrofibrils in the human scalp hair cortex

55 citations , February 2014 in “Journal of Structural Biology”

This study observed that human hair macrofibrils predominantly exhibit a double-twist architecture with varying inter-macrofibril angles, advancing insights into their structural organization and mechanical implications.

research Human scalp hair as a thermoregulatory adaptation

21 citations , June 2023 in “Proceedings of the National Academy of Sciences”

This study found that human scalp hair significantly reduces solar radiation intake, with more tightly curled hair offering greater protection against heat gain compared to a naked scalp.

research Single-cell transcriptomics reveals lineage trajectory of human scalp hair follicle and informs mechanisms of hair graying

13 citations , May 2022 in “Cell discovery”

This study used single-cell RNA sequencing to create a detailed atlas of human scalp hair follicles and found that early-stage hair graying involves matrix hair progenitor depletion linked to P53 pathway activation.

research Hydroxylation of dehydroepiandrosterone in human scalp hair folhcles

11 citations , June 1979 in “British Journal of Dermatology”

This study found that the dehydroepiandrosterone hydroxylating enzyme system in hair follicles is similar to the liver monooxygenase system, sharing characteristics such as inhibition by carbon monoxide and dependency on NADPH.

View more "human scalp hair" in research →

Community Join

5 / 1000+ results

community Using topicals after hair transplant if safe to do so

5 upvotes 4 months ago

After a hair transplant, it's advised to stop using RU58841 and minoxidil to avoid irritation, resuming them 25-30 days post-surgery if the scalp is healed. The user is currently using finasteride, minoxidil, and RU58841, but there are concerns about the safety and efficacy of RU58841 in humans.

community From basically bald to brushing, showering, swimming, and sleeping on it like real hair

in Technology 12 upvotes 8 months ago

A user shared their experience with a hair restoration method involving adding individual human hairs on ultra-fine strands between existing hair, allowing for natural movement and appearance without blocking the scalp. They also continue using rosemary oil and gentle massage for basic growth support.

community Chinese reseachers successfully create hair follicles in-vitrofor autologous transplantation in vivo

29 upvotes 1 year ago

Chinese researchers have successfully created hair follicles in vitro, potentially offering unlimited hair for transplantation and a cure for hair loss. They plan to test these follicles in vivo on human scalps.

community Scalp testosterone does NOT cause hair loss, what is this baseless claim ?

in Research/Science 13 upvotes 5 months ago

DHT, not testosterone, causes hair loss. Treatments like finasteride, dutasteride, and RU58841 target DHT to manage hair loss.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

View more "human scalp hair" in community →

Learn

10 / 23 results

learn sh-Polypeptide-7

How does sh-Polypeptide-7 help stimulate hair follicle activity or reduce scalp inflammation? sh-Polypeptide-7 is the INCI name for a lab-made form of human growth hormone (somatotropin) — not EGF, which is sh-Oligopeptide-1. Growth hormone and IGF-1 signalling is documented in hair follicle biology, but there is no published human trial of sh-Polypeptide-7 applied to the scalp for hair growth or scalp inflammation.

learn Fluocinolone

Is Fluocinolone a treatment for hair loss itself or just for calming scalp irritation? Fluocinolone acetonide is a prescription corticosteroid approved for inflammatory skin conditions, not for hair loss; no published human trial has measured hair regrowth with it, so at most it may help indirectly by calming an inflamed scalp.

learn Hydrocortisone

When should hydrocortisone be used for hair loss — is it only for irritated scalps or also alopecia areata? Hydrocortisone is a low-potency topical steroid whose labelled use is calming scalp irritation such as dermatitis; for alopecia areata no verified human trial supports it on its own, and dermatologists generally use stronger prescription corticosteroids instead.

learn Latanoprost

How long does it usually take to see results from latanoprost for hair growth? There is no established timeline: the only human scalp trial, a 16-man pilot, measured a hair-density increase at 24 weeks using latanoprost 0.1% — twenty times the strength of the glaucoma eye drop — and faster figures quoted elsewhere come from eyelash and animal observations. Scalp use is off-label and experimental.

learn Bicalutamide

What results can you expect from using bicalutamide on your scalp? There is no published human study of bicalutamide applied to the scalp for hair loss, no licensed topical product and no established dose, so no result can be predicted from it. The evidence that exists is for the oral tablet in women, which is a prescription drug requiring liver monitoring and contraindicated in pregnancy.

learn Bimatoprost

a synthetic prostamide used to treat eyelashes also shows promise for stimulating hair growth on scalp

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Peppermint

herb and oil thought to stimulate skin and hair

learn GHK-Cu

a copper peptide showing promise in both regrowth and reversing gray hair

View more "human scalp hair" in learn →

Clinics

6 / 12 results

All 12 clinic results →

Experts

1 / 1 results

24
Trichologist
Kirsten J. Scalp
Greenville, SC, United States

Kirsten J. Scalp