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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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a copper peptide showing promise in both regrowth and reversing gray hair
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research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Toll-Like Receptor 3 Agonist, Polyinosinic-Polycytidylic Acid, Upregulates Carbonic Anhydrase II in Human Keratinocytes
A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.
research The Effects of Finasteride on Hair Growth, Hair Cycle Stage, and Serum Testosterone and Dihydrotestosterone in Adult Male and Female Stumptail Macaques
Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
Community Join
5 / 1000+ resultscommunity Has anyone ever used grape seed extract? Any negative effects on hair ?
The conversation is about the effects of grape seed extract on hair, with mixed experiences reported. One user advises against using it.
community 4 months of topical minoxidil with derma rolling starting at month 2 - my review / experience
The user has been using topical minoxidil and dermarolling for hair regrowth but is hesitant to start finasteride due to potential side effects. Many suggest adding finasteride for better results in addressing DHT-related hair loss.
community Please can someone explain all the Dutasteride horror stories on here
Switching from finasteride to dutasteride for hair loss yields mixed results, with some users experiencing improvements and others facing worsening conditions or side effects like shedding. Patience is advised as dutasteride may take longer to show results, and combining treatments is suggested by some users.
community Dutasteride is my last Hope ??
User tried topical and oral finasteride and oral minoxidil for hair loss without success. ButterscotchSea3159 suggests using Dutasteride, oral minoxidil, ketoconazole shampoo, microneedling, and possibly RU for better results.
community Study shows further evidence that finasteride and dutasteride take 12-18 months or more to show significant results. Do NOT give up early
The conversation discusses the effectiveness of finasteride and dutasteride in treating hair loss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.