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research Exploring the effect of hsa-miR-19b-3p on IL-1R1 expression and serum levels in alopecia areata

1 citations , January 2025 in “Archives of Dermatological Research”

This study found that patients with alopecia areata had significantly higher serum IL-1R1 levels, IL-1R1 gene expression, and hsa-miR-19b-3p levels compared to healthy controls, suggesting these could serve as diagnostic and prognostic markers for the disease's severity.

research rs4541843 G > A variant near miR-182 is associated with susceptibility, severity, and increased hsa-miR-182-5p expression in alopecia areata

June 2026 in “Archives of Dermatological Research”

In this study, the rs4541843 G > A variant was found to be significantly associated with increased risk and severity of alopecia areata, as well as elevated expression of hsa-miR-182-5p, suggesting their potential as molecular markers for diagnosis and severity assessment.

research Correction to “the Role of Hsa‐miR‐193a‐5p as an Important Factor for Control of Inositol in Alopecia Areata”

July 2025 in “Skin Research and Technology”

Hsa-miR-193a-5p is important in alopecia areata by promoting inflammation and involving specific genes in hair and immune function.

research The role of hsa‐miR‐193a‐5p as an important factor for control of inositol in alopecia areata

June 2024 in “Skin Research and Technology”

This study observed that the expression of hsa-miR-193a-5p was significantly higher in alopecia areata patients compared to healthy controls, suggesting its role in influencing disease progression through impact on specific signaling pathways and highlighting its potential as a therapeutic target.

research Myocyte Androgen Receptor Modulates Body Composition and Metabolic Parameters

December 2010 in “TSpace”

In this study, selective overexpression of androgen receptors in muscle cells increased lean muscle mass and reduced fat mass in transgenic rodents, suggesting a potential target for drug development.

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5 / 7 results

community : 3-Year Transformation: How adding an LLLT Cap finally stabilized my 200+ hair/day shed (Fin/Min/Niz/LLLT)

322 upvotes 5 months ago

Adding an LLLT laser cap to a routine of finasteride, minoxidil, and ketoconazole shampoo significantly reduced hair shedding from 200+ hairs a day to around 80, improving scalp health. The user attributes the laser cap as the key factor in stabilizing hair loss after two years of using other treatments.

community Best red light hair therapy device for someone already on min and fin? Looking to add LLLT to my stack.

in Technology 12 upvotes 4 months ago

The user is considering adding low-level laser therapy (LLLT) to their hair loss treatment routine, which already includes minoxidil, finasteride, and microneedling. They are debating between purchasing a cheaper LLLT device or investing in a more expensive, clinically-backed option, with concerns about the effectiveness and specifications of cheaper models.

community Been on Finasteride for 19 years

457 upvotes 11 months ago

A 49-year-old has used finasteride for 19 years to manage hair loss, experiencing some libido changes but no major side effects, and plans to continue. They found minoxidil inconvenient but are considering restarting it with micro-needling.

community If PP405 works it will be fkn impossible to buy it.

103 upvotes 10 months ago

PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

community 3 months fin/min progress (age 31)

in Progress Pictures 173 upvotes 2 years ago

A user shared their 3-month progress using 1mg oral finasteride daily and 5% topical minoxidil twice daily, along with Pura D’Or anti-thinning shampoo and a scalp massager. They noticed initial worsening but later saw hair follicle recovery.

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