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GlossaryC18 Column

used in HPLC to separate compounds by hydrophobic interactions

A C18 Column, also known as an Octadecylsilane (ODS) Column, is a type of High-Performance Liquid Chromatography (HPLC) column used for separating and analyzing compounds in a mixture. It is packed with silica particles bonded with long-chain hydrocarbons (18 carbon atoms), making it highly effective for separating non-polar to moderately polar compounds based on their hydrophobic interactions.

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Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry

research Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry

45 citations, August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Method detects finasteride in plasma and semen with high sensitivity and accuracy.

RP-HPLC Technique for Dutasteride Quantitative Estimation in Tablet Dosage Form: Formulation and Validation of Analytical Technique

research RP-HPLC Technique for Dutasteride Quantitative Estimation in Tablet Dosage Form: Formulation and Validation of Analytical Technique

January 2024 in “International Journal of Biological and Environmental Investigations”

A reliable method was developed to measure dutasteride in tablets accurately and consistently.

research In Vitro and In Vivo Assessment of Metabolic Drug Interaction Potential of Dutasteride with Ketoconazole

7 citations, December 2019 in “Pharmaceutics”

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

research Review of Fluconazole Properties and Analytical Methods for Its Determination

8 citations, July 2011 in “Critical reviews in analytical chemistry”

The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.

Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study

research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study

1 citations, April 2015 in “Drug research”

New method measures finasteride in plasma, finds two formulations bioequivalent.

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community RU58841, 8% HPLC-MS done by jano, they legit

in Research/Science 8 upvotes 3 years ago

The conversation is about testing the effectiveness of RU58841 for hair loss, with the user planning to increase their dose to 30 mg per day along with 20 mg of Minoxidil. The test results showed approximately 70 mg/ml, which the user considers a good result.

community Recovery from 2nd Dutasteride shed

in Update 16 upvotes 8 months ago

User switched from finasteride to dutasteride due to shedding, experienced two sheds, and now uses 5mg oral minoxidil, 0.5mg dutasteride, and 3ml oral castor oil daily. Hair has recovered from the second shed, and the user plans to maintain the current treatment.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Minoxidil, RU58841, CB-03-01, WAY-316606, and derma stamping.

in Minoxidil 5 upvotes 5 years ago

The user is using Minoxidil, RU58841, CB-03-01, WAY-316606, Ketoconazole, MK-677, and derma stamping to treat hair loss and has noticed new hair growth, especially around the temples and hairline. They apply different treatments at various times of the day and have seen improvements in skin condition and body hair texture.

community The New, Improved CB-03-01/Setipiprant Group Buy

29 upvotes 8 years ago

The group buy for CB-03-01, a topical anti-androgen for hair loss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.

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