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research Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production

7 citations , September 2022 in “Communications biology”

This research found that Leydig cells significantly rely on synthesizing omega-6 HUFAs to support male steroid hormone production, highlighting a new role for these fatty acids in the male reproductive system.

research Sebum Production

1 citations , September 2016 in “Springer eBooks”

This article reports no new data; it describes the role of sebum in influencing the skin microbiome and epithelial tissues and discusses its altered composition during transit through the sebaceous duct.

research Hair & Cutaneous Development

January 2012 in “Journal of Investigative Dermatology”

research Elevated Free Testosterone Levels in Women With Acne

56 citations , October 1983 in “Archives of Dermatology”

This study found that free testosterone levels were a more sensitive indicator of hyperandrogenism in women with acne than total testosterone levels.

research The Case of the Elusive Androgen

1 citations , November 2002 in “Endocrine practice”

This case report describes a post-menopausal woman with severe hirsutism whose high testosterone levels decreased after gonadotropin suppression, indicating residual hormone-producing tissue responsive to gonadotropins.

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community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

124 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Dear Dut users,have you noticed any metabolic changes with use of the drug?

6 upvotes 1 year ago

Dutasteride users have mixed results in hair loss treatment, with some experiencing improvements and others worsening. Some report metabolic changes like weight gain or diabetes, while others have no significant side effects.

community Had a hormone panel to determine if I’m in range to use finasteride without too many issues. Thoughts?

5 upvotes 3 years ago

A user shared their hormone levels to gauge if they can use finasteride for hair loss without issues. Their hormone levels are mostly within the reference ranges.

community M-28, did a few hormone blood tests since I want a baseline before starting Fin. DhT high. But also Estradiol? Why?

4 upvotes 5 years ago

A user discusses their hormone blood test results before starting finasteride for hair loss, noting high DHT and estradiol levels. They tried topical finasteride for a few days but felt tired.

community Finasteride influence on other hormones

8 upvotes 5 years ago

Finasteride can affect hormone levels, potentially causing symptoms like puffy nipples and testicular pain, and may result in elevated prolactin and high testosterone. The user is seeking interpretation of these changes after taking finasteride.

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Learn

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learn Centella

Sensitive to hormones? A centella scalp mask may help ease hidden inflamm Centella asiatica has anti-inflammatory and wound-healing effects in animal and cell studies, but no published research has tested a centella scalp mask on the human scalp, in hormonal contexts or otherwise, and no community reports were found of one being used this way.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

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