research Pituitary Macroprolactinoma With Mildly Elevated Serum Prolactin: Hook Effect
The man's symptoms improved and the tumor shrank after treatment with cabergoline.
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research The Shepherd's Hook Phenomenon Pattern of Hair Roots: A Demonstration of Comparative Bioelectromagnetism Between Human Hairs and Mouse Whiskers by Means of the Photoelectric Effect
Human hair and mouse whiskers emit similar biomagnetic fields.
research Prolactin and Hyperprolactinemia in Female Reproductive Endocrinology – An Update
Too much prolactin can cause menstrual problems, infertility, and sexual issues in women.
research Proteolysis-Targeting Chimera (PROTAC): Current Applications And Future Directions
Proteolysis-targeting chimeras (PROTACs) represent a significant advancement in targeted protein degradation, offering new therapeutic possibilities for previously "undruggable" targets. This review highlights the development of PROTACs across various therapeutic areas, focusing on key targets like kinases and hormone receptors. Notable candidates include ARV-110 for prostate cancer and ARV-471 for breast cancer, with clinical trials progressing to Phase III by 2024. Challenges such as the "hook effect" and oral bioavailability are discussed, alongside future directions like innovative delivery strategies and expanding E3 ligase repertoires. The review underscores the potential of PROTACs to transform treatments for complex diseases resistant to traditional therapies.
research Endocrine Disorders and Infertility
Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.
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5 / 52 resultscommunity Why visit Tressless if you actively despise medical treatment? (Fin/Dut/Min)
Finasteride, dutasteride, and minoxidil are discussed as effective hair loss treatments, with mixed opinions on their use and side effects. The conversation highlights a divide between supporting medical treatments and accepting baldness.
community Summaries of Finasteride Studies
Finasteride is effective in promoting hair growth and reversing hair miniaturization in men with androgenetic alopecia, with improvements seen in various studies over different durations. Some users report initial side effects like ball ache, which often resolve as the body adjusts.
community Been on Propecia since 1997, recently switched to Topical Finasteride.. follow for updates, or to ask any questions about 23 years on Propecia.
User spent 23 years on Finasteride with side effects like weight gain and reduced libido. Switched to topical Finasteride, side effects reduced and waiting for results.
community LLLT seems like it's at least a solid maintenance tool. Can also provide ok regrowth in AA and MPB. - Pubmed
Low-Level Laser Therapy (LLLT) is seen as a safe and effective method for maintaining hair and promoting regrowth in androgenetic alopecia (AGA) and male pattern baldness (MPB), with devices like the HairMax LaserComb® and iRestore helmet being popular. Some users and professionals are skeptical about its long-term effectiveness and cost.
community The homeless crackhead protocol
The conversation humorously suggests that drug use might be more effective for hair retention than traditional treatments like minoxidil or finasteride. It attributes full heads of hair in homeless individuals to lifestyle factors like reduced stress or hormonal changes.