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research Histologic Changes in the Skin of Hairless Mice Following Peeling With Salicylic Acid

74 citations , November 2000 in “Archives of Dermatology”

In this study, application of salicylic acid solution on mouse skin showed histologic changes without causing wounds or inflammation, observed immediately and up to 48 hours after treatment.

research Histologic Changes in Seborrheic Keratoses after Rubbing

13 citations , February 1980 in “Journal of Cutaneous Pathology”

This study observed that seborrheic keratosis lesions in five patients exhibited specific histological changes after trauma, suggesting a connection between these lesions and hair follicle structures.

research Histological changes of pre and postnatal Skin Development in Rats

January 2012

This study examined prenatal and postnatal development of rat skin, observing marked changes in epidermal thickness and collagen fiber distribution as the rats aged.

research Alopecia: histologic changes.

3 citations , January 1989 in “PubMed”

This paper discusses various histologic features to distinguish types of alopecia and reports no new clinical findings.

research Evaluation of Morphological and Histological Changes in Transplanted Hair Follicles

December 2023 in “International Journal of Medical Arts”

In this study, researchers observed significant morphological and histological differences in transplanted hair follicles compared to native donor follicles post-FUE hair transplantation for androgenetic alopecia, highlighting substantial variations in sebaceous gland and root sheath degeneration at the recipient site.

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community Blocking dht should bring it back. So why does fin mostly just hold the line?

17 upvotes 3 months ago

Finasteride mainly prevents further hair loss by blocking DHT but doesn't reverse existing damage, while minoxidil can promote regrowth by waking dormant follicles. Ketoconazole helps with inflammation, but none of these treatments can reverse fibrosis or structural changes around hair follicles.

community Microneedling Isn’t Snake Oil — It’s Evidence-Based. Let’s Talk Studies, Not Fear.

41 upvotes 1 year ago

Microneedling is supported by research as an effective adjuvant treatment for hair loss, especially when combined with Minoxidil or Finasteride, with minimal side effects if done properly. Concerns about long-term safety and potential risks like infection or fibrosis remain, but many users report positive results.

community Summaries of Finasteride Studies

in Research/Science 20 upvotes 1 year ago

Finasteride is effective in promoting hair growth and reversing hair miniaturization in men with androgenetic alopecia, with improvements seen in various studies over different durations. Some users report initial side effects like ball ache, which often resolve as the body adjusts.

community A new study by Deng and colleagues set out to explore differences between balding and non balding scalps...

39 upvotes 4 years ago

Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.

community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 1 year ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

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