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Did you mean Histological Changes?

GlossaryHistopathological Changes

microscopic tissue alterations due to disease or injury

Histopathological changes refer to the microscopic alterations in tissue structure and cellular composition that occur due to disease or injury. These changes are examined through a biopsy or tissue sample under a microscope, providing crucial information for diagnosing conditions like cancer, infections, or inflammatory diseases.

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community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community microneedle, any long term users damage?

in Microneedling 35 upvotes 6 months ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

community Should I just switch to oral minoxidil + where do you get cheap oral minoxidil in the United States?

in Minoxidil 19 upvotes 2 months ago

Switching from topical to oral minoxidil due to scalp irritation and unsatisfactory results, while also seeking cheaper options in the U.S. Oral minoxidil is generally favored for its effectiveness and fewer application downsides, with CostPlusDrugs and GoodRx offering affordable prices.

community It works. About a 1 year transformation.

in Progress Pictures 613 upvotes 1 year ago

A user's experience with hair loss treatments, specifically Minoxidil and finasteride, which they have used without side effects for a year. Other users shared their experiences and advice about potential side effects and supplements to help.

community The theory that explains everything. The malloclusion theory has been proven.

in Research/Science 27 upvotes 1 year ago

Brian Dye's theory links skeletal malocclusion type II to hair loss, suggesting it's a blood flow issue. Treatments mentioned include minoxidil, finasteride, and anti-inflammatory drugs like benaxoprofen.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Verteporfin update - donor hair regeneration human trial

in Research/Science 23 upvotes 2 years ago

A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.