54 citations
,
March 1991 in “Proceedings of the National Academy of Sciences”
This study describes a gel-supported in vitro system for culturing skin samples that may effectively replace animal systems for toxicity testing, showing high correlation with in vivo skin toxicity measurements.
21 citations
,
October 2010 in “Encyclopedia of Life Sciences”
This article discusses the use of histoculture in cancer treatment, hair growth studies, and immune response research, but reports no new clinical results.
57 citations
,
February 1994 in “Experimental dermatology”
This study found that murine skin is a target for melatonin bioregulation, as melatonin affected DNA synthesis and tyrosinase activity in skin organ culture.
This study demonstrated that Gelfoam® histoculture supports extensive growth of both hair shafts and sensory nerves from isolated mouse whisker follicles over prolonged periods.