In this study, researchers found that finasteride induces dysregulation of genes related to neuropsychiatric disorders, including the HOMER-3 gene associated with dementia, and propose exploring craniosacral osteopathic therapy's potential to modulate this gene's methylation profile and alleviate related symptoms.
In this study, young adult male albino rats treated with finasteride showed a 10% reduction in thickness of the CA1 layer of the hippocampus, suggesting that this atrophy may contribute to memory impairments linked to Post-Finasteride Syndrome.
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June 2014 in “American Journal of Men's Health” This study highlights that adverse effects from finasteride may persist in men after discontinuation, indicating a potential "post-finasteride syndrome.
June 2026 in “Reports of Morphology” This study on female Wistar rats with stress-induced alopecia found that a modified diet rich in antioxidants and nutrients reduced dystrophic skin changes and preserved the functional activity of hair follicles, suggesting dietary approaches may support hair restoration under chronic stress conditions.
September 2025 in “Sahel Journal of Life Sciences FUDMA” This study reported that albino Wistar rats exposed to chemical hair straighteners showed significant hair fiber damage and scalp skin deterioration, which worsened with repeated and prolonged application, highlighting the cytotoxic potential of these products and potential systemic risks.