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    GlossaryHighly Active Antiretroviral Therapy

    treatment for HIV/AIDS using multiple antiretroviral drugs

    Highly Active Antiretroviral Therapy (HAART) is a treatment regimen for HIV/AIDS that uses a combination of three or more antiretroviral drugs to suppress the virus and stop its progression. This approach reduces the viral load in the body to undetectable levels, improves immune function, and decreases the risk of HIV transmission.

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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

    Research

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      Skin Disease in Korean HIV Patients

      research Skin Disease in Korean HIV Patients

      January 2019 in “Annals of Dermatology”
      HIV patients in Korea often have skin diseases like fungal infections, folliculitis, and seborrheic dermatitis, which are less common with effective HIV treatment.
      HIV Infection Mimicking Autoimmune Disorder

      research HIV Infection Mimicking Autoimmune Disorder

      1 citations, August 2007 in “Indian Journal of Pediatrics”
      A girl with symptoms like an autoimmune disorder actually had HIV and a fungal infection, which was hard to diagnose and treat, leading to her death.
      Hair Loss Induced by Lopinavir-Ritonavir

      research Hair Loss Induced by Lopinavir-Ritonavir

      7 citations, July 2007 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy”
      The medication lopinavir-ritonavir may cause severe hair loss.

    Community Join

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      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  56 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community Losing hair for 3 years (24 yrs old)

      in Chat  26 upvotes 3 years ago
      User losing hair for 3 years tried shampoos, minoxidil, derma rolling, finasteride, and Adegen's 15% minoxidil protocol without success. Another user suggests lowering finasteride dosage and trying topical non-steroidal anti-androgens like Fluridil, RU58841, and Breezula.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  736 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.