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GlossaryAdeno-Associated Virus

small virus used in gene therapy for precise genetic delivery

Adeno-Associated Virus (AAV) is a small virus that infects humans but is not known to cause disease. It is commonly used in gene therapy because it can deliver genetic material into cells with high precision and low immune response.

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research Development of Gene Therapy for Inner Ear Disease: Using Bilateral Vestibular Hypofunction as a Vehicle for Translational Research

28 citations, January 2011 in “Hearing Research”

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds

6 citations, June 2019 in “Biotechnology Letters”

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

research More Than One Way to Skin a Wound: A Novel Regenerative Approach for Healing Non-Healing Cutaneous Ulcers

2 citations, November 2018 in “Cell Stem Cell”

The research found a new way to heal chronic skin ulcers by turning certain cells into skin tissue using specific factors.

research In Vivo Reprogramming of Wound-Resident Cells Generates Skin with Hair

March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Scientists can now create skin with hair by reprogramming cells in wounds.

research CaBP1 and 2 Enable Sustained CaV1.3 Calcium Currents and Synaptic Transmission in Inner Hair Cells

January 2024

CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.

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community Topical Dutasteride 1% - High dosage?

in Finasteride/Dutasteride 6 upvotes 2 years ago

User asks about two topical dutasteride solutions and wonders if 1% concentration is overkill compared to 0.1%. They also consider trying standard topical dutasteride before using Minoxidil.