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Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

The research found a new way to heal chronic skin ulcers by turning certain cells into skin tissue using specific factors.

Scientists can now create skin with hair by reprogramming cells in wounds.

CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.

The document is a detailed medical reference on skin and genetic disorders.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Increasing Wnt10b levels can help grow new hair follicles in mice.

The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.

Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.

The microbiome may be linked to hair loss and could be a target for new treatments.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Muscles and nerves that cause goosebumps also help control hair growth.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.