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research The laboratory in the multidisciplinary diagnosis of differences or disorders of sex development (DSD)

July 2021 in “Advances in laboratory medicine”

This article reviews differential diagnosis approaches for 46,XY DSD, proposing a diagnostic algorithm focused on biochemical and genetic data, without presenting new clinical results.

research Table 1_A partially automated method for DNA extraction from marmoset hair follicles to avoid blood chimerism.xlsx

September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

In this study, researchers developed a non-invasive, partially automated protocol for extracting DNA from marmoset hair follicles, resulting in high-quality whole genome sequencing with low chimerism levels, making it a reliable method compared to blood DNA sequencing in these primates.

research Data Sheet 1_A partially automated method for DNA extraction from marmoset hair follicles to avoid blood chimerism.docx

September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

This study developed a partially automated protocol utilizing hair follicles for DNA extraction in marmosets, achieving reliable whole genome sequencing with low chimerism, offering an efficient alternative to blood for genetic studies in non-human primates.

research High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata

46 citations , October 2018 in “JCI insight”

In this study, the researchers found that treatment with the JAK inhibitor tofacitinib in alopecia areata patients may reduce clonal CD8+ T cell expansions but does not eliminate them entirely, which could contribute to disease relapse.

research High-throughput Sequencing to Identify Monogenic Etiologies in a Preselected Polycystic Ovary Syndrome Cohort

2 citations , July 2022 in “Journal of the Endocrine Society”

This study identified several rare genetic variants related to insulin resistance in women with PCOS, highlighting the potential for monogenic conditions in patients with extreme or atypical phenotypes.

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community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 2 years ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community A Theory on Why Microneedling Works

175 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community How do I not kill my partners cat while using minoxidil ?

in Minoxidil 156 upvotes 9 months ago

Minoxidil is toxic to cats, so users should wash hands after application and ensure it dries before pets are near. Some switch to oral minoxidil to avoid risks, while others use topical forms cautiously.

community The Health Benefits of Head Hair

in Research/Science 19 upvotes 11 months ago

Hair provides protection against head trauma, reduces skin cancer risk, helps remove heavy metals, and aids in wound healing. The conversation emphasizes the health benefits of maintaining head hair beyond cosmetic reasons.

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Clinics

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SMP Specialist
Craig Bottomley-High
Studham, England, United Kingdom
13+ yrs

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Craig Bottomley-High