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This study observed that mice with a whole-body deficiency of Cystathionine-β-synthase developed severe hyperhomocysteinemia and related mild symptoms without increased mortality, indicating HHCy may not directly cause end organ damage.

This article suggests that alopecia areata may be an early skin manifestation of hereditary hemochromatosis in individuals predisposed to autoimmunity, recommending iron status evaluation during AA diagnosis; it reports no new clinical results.

This study suggests elevated homocysteine levels may serve as a biomarker for disease severity and vascular risk in cutaneous lupus erythematosus, indicating potential therapeutic benefits from B-vitamin supplementation and lifestyle changes.